Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …

Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …

Hydrogels with adhesive properties have potential for numerous biomedical applications.
Here, the design of a novel, intrinsically adhesive hydrogel and its use in developing internal …

Genome-wide association studies (GWASs) have discovered numerous risk genes for
Alzheimer's disease (AD), but how these genes confer AD risk is challenging to decipher. To …

Anxiety disorders are the most prevalent mental disorders. However, the genetic etiology of
anxiety disorders remains largely unknown. Here we conducted a genome-wide meta …

Schizophrenia and bipolar disorder are disabling psychiatric disorders with a worldwide
prevalence of approximately 1%. Both disorders present chronic and deteriorating …

The burden of human disease lies predominantly in polygenic diseases. Since the early
2000s, genome-wide association studies (GWAS) have identified genetic variants and loci …

A major challenge of genome-wide association studies (GWASs) is to translate phenotypic
associations into biological insights. Here, we integrate a large GWAS on blood lipids …

Identifying genes whose expression is associated with schizophrenia (SCZ) risk by
transcriptome-wide association studies (TWAS) facilitates downstream experimental studies …

Background Previous genome-wide association studies (GWAS) have identified numerous
risk genes for lacunar stroke, but it is challenging to decipher how they confer risk for the …