Update on treatments for nonmotor symptoms of Parkinson's disease—an evidence‐based medicine review

K Seppi, K Ray Chaudhuri, M Coelho… - Movement …, 2019 - Wiley Online Library
Objective To update evidence‐based medicine recommendations for treating nonmotor
symptoms in Parkinson's disease (PD). Background The International Parkinson and …

[HTML][HTML] Circuit mechanisms of Parkinson's disease

MM McGregor, AB Nelson - Neuron, 2019 - cell.com
Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …

[HTML][HTML] Neuroimaging evidence of glymphatic system dysfunction in possible REM sleep behavior disorder and Parkinson's disease

X Si, T Guo, Z Wang, Y Fang, L Gu, L Cao… - npj Parkinson's …, 2022 - nature.com
Alpha-synucleinopathy is postulated to be central to both idiopathic rapid eye movement
sleep behaviour disorder (iRBD) and Parkinson's disease (PD). Growing evidence suggests …

[HTML][HTML] The biology of REM sleep

J Peever, PM Fuller - Current biology, 2017 - cell.com
Considerable advances in our understanding of the mechanisms and functions of rapid-eye-
movement (REM) sleep have occurred over the past decade. Much of this progress can be …

New evidence on the management of Lewy body dementia

JP Taylor, IG McKeith, DJ Burn, BF Boeve… - The Lancet …, 2020 - thelancet.com
Dementia with Lewy bodies and Parkinson's disease dementia, jointly known as Lewy body
dementia, are common neurodegenerative conditions. Patients with Lewy body dementia …

[HTML][HTML] Appropriate use criteria for lumbar puncture and cerebrospinal fluid testing in the diagnosis of Alzheimer's disease

LM Shaw, J Arias, K Blennow, D Galasko… - Alzheimer's & …, 2018 - Elsevier
Abstract Introduction The Alzheimer's Association convened a multidisciplinary workgroup to
develop appropriate use criteria to guide the safe and optimal use of the lumbar puncture …

Parkinson's disease psychosis: presentation, diagnosis and management

RB Schneider, J Iourinets, IH Richard - Neurodegenerative …, 2017 - Taylor & Francis
Parkinson's disease is a neurodegenerative disorder characterized by motor and nonmotor
symptoms. Psychosis is a common feature of Parkinson's disease. Parkinson's disease …

REM sleep behavior disorder: diagnosis, clinical implications, and future directions

EK St Louis, BF Boeve - Mayo Clinic Proceedings, 2017 - Elsevier
Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of
dream enactment accompanied by polysomnographic rapid eye movement sleep atonia …

[HTML][HTML] Research evidence of the role of the glymphatic system and its potential pharmacological modulation in neurodegenerative diseases

JP Verghese, A Terry, ER de Natale… - Journal of Clinical …, 2022 - mdpi.com
The glymphatic system is a unique pathway that utilises end-feet Aquaporin 4 (AQP4)
channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid …

[HTML][HTML] Neuroprotective effect of melatonin on Sleep disorders Associated with Parkinson's Disease

X Hu, J Li, X Wang, H Liu, T Wang, Z Lin, N Xiong - Antioxidants, 2023 - mdpi.com
Parkinson's disease (PD) is a complex, multisystem disorder with both neurologic and
systemic manifestations, which is usually associated with non-motor symptoms, including …