Neuroinflammation and central sensitization in chronic and widespread pain
Chronic pain is maintained in part by central sensitization, a phenomenon of synaptic
plasticity, and increased neuronal responsiveness in central pain pathways after painful …
plasticity, and increased neuronal responsiveness in central pain pathways after painful …
[HTML][HTML] An overview of animal models of pain: disease models and outcome measures
NS Gregory, AL Harris, CR Robinson, PM Dougherty… - The journal of pain, 2013 - Elsevier
Pain is ultimately a perceptual phenomenon. It is built from information gathered by
specialized pain receptors in tissue, modified by spinal and supraspinal mechanisms, and …
specialized pain receptors in tissue, modified by spinal and supraspinal mechanisms, and …
Biochemicals associated with pain and inflammation are elevated in sites near to and remote from active myofascial trigger points
JP Shah, JV Danoff, MJ Desai, S Parikh… - Archives of physical …, 2008 - Elsevier
Shah JP, Danoff JV, Desai MJ, Parikh S, Nakamura LY, Phillips TM, Gerber LH.
Biochemicals associated with pain and inflammation are elevated in sites near to and …
Biochemicals associated with pain and inflammation are elevated in sites near to and …
Neurotrophins: mediators and modulators of pain
S Pezet, SB McMahon - Annu. Rev. Neurosci., 2006 - annualreviews.org
The neurotrophin family of neurotrophic factors are well-known for their effects on neuronal
survival and growth. Over the past decade, considerable evidence has accumulated from …
survival and growth. Over the past decade, considerable evidence has accumulated from …
An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle
JP Shah, TM Phillips, JV Danoff… - Journal of applied …, 2005 - journals.physiology.org
Myofascial pain associated with myofascial trigger points (MTrPs) is a common cause of
nonarticular musculoskeletal pain. Although the presence of MTrPs can be determined by …
nonarticular musculoskeletal pain. Although the presence of MTrPs can be determined by …
Massage therapy attenuates inflammatory signaling after exercise-induced muscle damage
Massage therapy is commonly used during physical rehabilitation of skeletal muscle to
ameliorate pain and promote recovery from injury. Although there is evidence that massage …
ameliorate pain and promote recovery from injury. Although there is evidence that massage …
Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development?
Pain is one of the classical signs of the inflammatory process in which sensitization of the
nociceptors is the common denominator. This sensitization causes hyperalgesia or allodynia …
nociceptors is the common denominator. This sensitization causes hyperalgesia or allodynia …
The effects of cold water immersion and active recovery on inflammation and cell stress responses in human skeletal muscle after resistance exercise
Key points Cold water immersion and active recovery are common post‐exercise recovery
treatments. A key assumption about the benefits of cold water immersion is that it reduces …
treatments. A key assumption about the benefits of cold water immersion is that it reduces …
TNF-alpha contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2
Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine. It is generally
believed that TNF-α exerts its effects primarily via TNF receptor subtype-1 (TNFR1). We …
believed that TNF-α exerts its effects primarily via TNF receptor subtype-1 (TNFR1). We …
Differential expression patterns of cytokines in complex regional pain syndrome
Complex regional pain syndromes (CRPS) are characterized by persistent and severe pain
after trauma or surgery. Neuro-immune alterations are assumed to play a pathophysiological …
after trauma or surgery. Neuro-immune alterations are assumed to play a pathophysiological …