Purpose Better understanding of pharmacokinetics of oral vinorelbine (VNR) in children
would help predicting drug exposure and, beyond, clinical outcome. Here, we have …

The purpose of this study was to analyze the drug interactions of paclitaxel (PTX) with
epirubicin (EPI), carboplatin (CBDCA), gemcitabine (GEM) and vinorelbine (VIN) in human …

Anti-vascular effects of the novel Vinca alkaloid, vinflunine have been investigated in the
MAC 15A transplantable murine colon adenocarcinoma model and compared with those …

Polyamines are essential for cell growth and differentiation. Structural polyamine analogues
have been shown to have antitumor activity in experimental models including breast cancer …

Persons over the age of 65 years are the fastest growing segment of the US population. In
the next 30 years this segment will represent more than 20% of the population. Fifty percent …

Background The long-term survival of patients with stage III non–small cell lung cancer
treated with a combination of chemotherapy and radiation is 10% to 20%. Survival could …

The fastest growing segment of the US population is the group over the age of 65 years. In
the next 30 years, this group will comprise over 20% of the population. Because 60% of all …

Abstract Purpose: Vinflunine (20′-20′-difluoro-3′, 4′-dihydrovinorelbine), a novel
derivative of vinorelbine characterized by marked antitumour activity in vivo in a series of …

Persons over the age of 65 years are the fastest growing segment of the United States
population. In the next 30 years it will comprise over 20% of the population. Fifty percent of …

OBJECTIVES.: To assess the activity of vinorelbine in women with recurrent or resistant
epithelial ovarian cancer following treatment with platinum and paclitaxel in terms of survival …