Clickable styryl dyes for fluorescence labeling of pyrrolidinyl PNA probes for the detection of base mutations in DNA

B Ditmangklo, J Taechalertpaisarn… - Organic & …, 2019 - pubs.rsc.org
Fluorescent hybridization probes are important tools for rapid, specific and sensitive analysis
of genetic mutations. In this work, we synthesized novel alkyne-modified styryl dyes for …

Bright red-emitting highly reliable styryl probe with large stokes shift for visualizing mitochondria in live cells under wash-free conditions

CS Abeywickrama, KJ Wijesinghe, RV Stahelin… - Sensors and Actuators B …, 2019 - Elsevier
Bright red-emitting pyridinium cyanine based styryl probe 2 is synthesized in good yields.
Probe 2 demonstrated a large Stokes' shift (Δλ≈ 128 nm, 4227 cm− 1 in DCM) and excellent …

[HTML][HTML] Strand displacement and duplex invasion into double-stranded DNA by pyrrolidinyl peptide nucleic acids

PR Bohländer, T Vilaivan… - Organic & Biomolecular …, 2015 - pubs.rsc.org
The so-called acpcPNA system bears a peptide backbone consisting of 4′-substituted
proline units with (2′ R, 4′ R) configuration in an alternating combination with (2S)-amino …

Lighting Up the Thrombin-Binding Aptamer G-Quadruplex with an Internal Cyanine-Indole-Quinolinium Nucleobase Surrogate. Direct Fluorescent Intensity Readout …

MD Gray, PS Deore, AJ Chung… - Bioconjugate …, 2020 - ACS Publications
Fluorescent nucleobases represent an important class of molecular reporters of nucleic acid
interactions. In this work, the advantages of utilizing a noncanonical fluorescent nucleobase …

Bright and photostable cyanine-styryl chromophores with green and red fluorescence colour for DNA staining

PR Bohlaender, HA Wagenknecht - Methods and applications in …, 2015 - iopscience.iop.org
The synthesis and optical characterisation of a series of green-and red-emitting cyanine and
cyanine-styryl dyes is presented that were developed based on the cyanine-indole …

[HTML][HTML] Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono-and distyryl dye libraries

X Xie, M Zuffo, MP Teulade-Fichou… - Beilstein Journal of …, 2019 - beilstein-journals.org
A library of 52 distyryl and 9 mono-styryl cationic dyes was synthesized and investigated
with respect to their optical properties, propensity to aggregation in aqueous medium, and …

Acridine orange coated magnetic nanoparticles for nucleus labeling and DNA adsorption

CH Liu, SL Sahoo, MH Tsao - Colloids and Surfaces B: Biointerfaces, 2014 - Elsevier
The magnetic–fluorescent nanoparticles are the integration of fluorophores and magnetic
nanoparticles (MNP), which are superior to traditional single-modal nanoparticles. Here, we …

Key Structural Elements of Unsymmetrical Cyanine Dyes for Highly Sensitive Fluorescence Turn‐On DNA Probes

K Uno, T Sasaki, N Sugimoto, H Ito… - Chemistry–An Asian …, 2017 - Wiley Online Library
Unsymmetrical cyanine dyes, such as thiazole orange, are useful for the detection of nucleic
acids with fluorescence because they dramatically enhance the fluorescence upon binding …

Tuning the selectivity of N-alkylated styrylquinolinium dyes for sensing of G-quadruplex DNA

MQ Wang, J Xu, L Zhang, Y Liao, H Wei, YY Yin… - Bioorganic & Medicinal …, 2019 - Elsevier
Selective and sensitive detection of G-quadruplex DNA structures is an important issue and
attracts extensive interest. To this end, numerous small molecular fluorescent probes have …

[HTML][HTML] Effective synthesis, development and application of a highly fluorescent cyanine dye for antibody conjugation and microscopy imaging

DS Kovács, B Kontra, B Chiovini, D Müller… - Organic & …, 2023 - pubs.rsc.org
An asymmetric cyanine-type fluorescent dye was designed and synthesized via a versatile,
multi-step process, aiming to conjugate with an Her2+ receptor specific antibody by an azide …