Prognostic and predictive molecular markers in cholangiocarcinoma

S Pavicevic, S Reichelt, D Uluk, I Lurje, C Engelmann… - Cancers, 2022 - mdpi.com
Simple Summary Cholangiocarcinoma (CCA) is a heterogenous and aggressive
malignancy of the intra-and extrahepatic biliary tract, marked by a steeply rising incidence …

Surgical management of intrahepatic cholangiocarcinoma

DB Hewitt, ZJ Brown, TM Pawlik - Expert review of anticancer …, 2022 - Taylor & Francis
Introduction Intrahepatic cholangiocarcinoma (ICC) incidence continues to rise worldwide,
and overall survival remains poor. Complete surgical resection remains the only opportunity …

Feasibility of machine learning-based modeling and prediction using multiple centers data to assess intrahepatic cholangiocarcinoma outcomes

SN Zhou, DW Jv, XF Meng, JJ Zhang, C Liu… - Annals of …, 2023 - Taylor & Francis
Background and aims Currently, there are still no definitive consensus in the treatment of
intrahepatic cholangiocarcinoma (iCCA). This study aimed to build a clinical decision …

Hepatitis B virus-related intrahepatic cholangiocarcinoma originates from hepatocytes

Z Song, S Lin, X Wu, X Ren, Y Wu, H Wen, B Qian… - Hepatology …, 2023 - Springer
Abstract Background Hepatitis B virus (HBV) infection is one of the most common risk factors
for intrahepatic cholangiocarcinoma (ICC). However, there is no direct evidence of a causal …

Tumor burden score stratifies prognosis of patients with intrahepatic cholangiocarcinoma after hepatic resection: a retrospective, multi-institutional study

H Li, R Liu, H Qiu, Y Huang, W Liu, J Li, H Wu… - Frontiers in …, 2022 - frontiersin.org
Background The prognostic significance of tumor burden score (TBS) on patients who
underwent curative-intent resection of intrahepatic cholangiocarcinoma (ICC) has not been …

Defining and predicting early recurrence after resection for gallbladder cancer

K Sahara, DI Tsilimigras, Y Kikuchi, CG Ethun… - Annals of Surgical …, 2021 - Springer
Background The optimal time interval to define early recurrence (ER) among patients who
underwent resection of gallbladder cancer (GBC) is not well defined. We sought to develop …

Defining the risk of early recurrence following curative-intent resection for distal cholangiocarcinoma

K Sahara, DI Tsilimigras, J Toyoda, K Miyake… - Annals of surgical …, 2021 - Springer
Background Although multidisciplinary treatments including the use of adjuvant therapy (AT)
have been adopted for biliary tract cancers, patients with distal cholangiocarcinoma (DCC) …

Annals of surgical oncology practice guidelines series: Management of primary liver and biliary tract cancers

SM Ruff, JM Cloyd, TM Pawlik - Annals of Surgical Oncology, 2023 - Springer
Primary cancers of the liver and biliary tract are rare and aggressive tumors that often
present with locally advanced or metastatic disease. For patients with localized disease …

Comparison of current guidelines and consensus on the management of patients with cholangiocarcinoma: 2022 update

X Zhang, Y Cai, X Xiong, A Liu, R Zhou… - Intractable & Rare …, 2022 - jstage.jst.go.jp
As a consequence of breakthroughs in the area of guidelines research, the therapy for
cholangiocarcinoma has significantly improved the efficacy rate of diagnosis and survival …

[HTML][HTML] Biomarkers of intrahepatic cholangiocarcinoma: diagnosis and response to therapy

ZJ Brown, DB Hewitt, TM Pawlik - Frontiers in Bioscience-Landmark, 2022 - imrpress.com
Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer
behind hepatocellular carcinoma (HCC) and carries a dismal prognosis. Improved genetic …