Cooling Down Inflammation in the Cardiovascular System via the Nicotinic Acetylcholine Receptor

A Kaplan, B Lakkis, L El-Samadi… - Journal of …, 2022 - journals.lww.com
Inflammation is a major player in many cardiovascular diseases including hypertension,
atherosclerosis, myocardial infarction, and heart failure. In many individuals, these …

Toluenin toksisitesine karşı resveratrolün koruyucu etkisinin detoksifikasyon enzimlerı ile araştırılması

B Farahi - 2023 - acikerisim.uludag.edu.tr
Toluen, plastik üretimi, kimyasal sentez ve benzin üretimi dahil olmak üzere birçok
endüstriyel proseste yaygın olarak kullanılan organik bir çözücüdür. Tolueninmetabolizmasi …

OPEN ACCESS EDITED BY

X Zhang, Z Liu, E Soule, W Fan, L Shen… - … of Cancer: Novel …, 2024 - books.google.com
A large amount of evidence from literature has manifested that tumor cells can effectively
avoid being recognized and killed by the immune system through immune checkpoint …

Screening Biophysical Sensors and Actuators that Influence Wound Healing in Human Induced Pluripotent Stem Cell-Derived Neurons

V Pai, B Cooper, M Levin - 2022 - preprints.org
All living cells maintain a charge distribution across their cell membrane (membrane
potential) by carefully controlled ion fluxes. These bioelectric signals regulate cell behavior …

Elucidating TFEB's Role in Transcriptional Regulation of Macrophage Phenotype and Response

HH Honwad - 2024 - repository.escholarship.umassmed …
Diverse inputs dictate macrophage transcriptional programming that impacts activation and
relevant function, under homeostatic and disease conditions. My work addresses how stress …

Lumbriculus variegatus: Investigating a Novel in vivo Model for Substances of Abuse

R Mahmood - 2024 - cronfa.swan.ac.uk
To replace, reduce and refine using vertebrates in pharmacological research, invertebrate in
vivo models are required to continue investigating pharmacology in whole animal systems …

Exploring Human Safe Compounds for Treatment in Type 1 Diabetes

R Fitzpatrick, T Jetton - 2023 - scholarworks.uvm.edu
Diabetes involves the loss of functional pancreatic ß-cells, the source of insulin production in
the body. Many treatments for diabetes exist including multiple forms of insulin injection …

3D QSAR based Virtual Screening of Flavonoids as Acetylcholinesterase Inhibitors

S Andole, H Sd, S Sudhula, L Vislavath… - Worldwide Congress on …, 2022 - Springer
In an attempt to develop therapeutic agents to treat Alzheimer's disease, a series of
flavonoid analogues were collected, which already had established acetylcholinesterase …

[PDF][PDF] Effects of Choline Alphoscerate on neurotoxicity in a model of Alzheimer's disease

PGC Tarro - 2023 - iris.unict.it
Alzheimer's disease (AD) is the most common cause of dementia worldwide, characterized
by extreme unmet needs and a huge disease burden. Cerebral atrophy, amyloid plaques …

[PDF][PDF] Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer's

E Costantini, C Carrarini, P Borrelli, M De Rosa… - 2023 - immunityageing.biomedcentral.com
Background The diffuse distribution of nicotinic cholinergic receptors (nAChRs) in both brain
and peripheral immune cells points out their involvement in several pathological conditions …