Echinococcosis is a zoonosis caused by cestodes of the genus Echinococcus (family
Taeniidae). This serious and near-cosmopolitan disease continues to be a significant public …

Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Background Schistosomiasis is a disease that significantly impacts human health in the
developing world. Effective diagnostics are urgently needed for improved control of this …

Circulating tumor DNA (ctDNA) is a component of cell-free DNA that is shed by malignant
tumors into the bloodstream and other bodily fluids. Levels of ctDNA are typically low …

The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

Metagenomic next-generation sequencing (mNGS) of microbial cell-free DNA (mcfDNA
sequencing) is becoming an attractive diagnostic modality for infectious diseases, allowing …

Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …

Background Extrachromosomal circular deoxyribonucleic acid (eccDNA) is evolving as a
valuable biomarker, while little is known about its presence in urine. Methods Here, we …

Background Parasitic diseases are one of the world's most devastating and prevalent
infections, causing millions of morbidities and mortalities annually. In the past, many of these …

Schistosomiasis is a debilitating disease affecting over 200 million people, with the highest
burden of morbidity and mortality in African countries. Despite its huge impact on the health …