Flavonoids are a class of bioactive phytochemicals containing a core 2-phenylchromone
skeleton and are widely found in fruits, vegetables, and herbs. Such natural compounds …

Systemic candidiasis is a common, high-mortality, nosocomial fungal infection.
Unexpectedly, it has emerged as a complication of anti-complement C5-targeted …

Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

Recognition of pathogen-associated molecular patterns can trigger the inositol-requiring
enzyme 1 α (IRE1α) arm of the endoplasmic reticulum (ER) stress response in innate …

Chronic kidney disease (CKD) has become a global public health problem with high
morbidity and mortality. Renal fibrosis can lead to end-stage renal disease (ESRD) …

Protection against lethal Candida albicans (Ca)/Staphylococcus aureus (Sa) intra-
abdominal infection (IAI)-mediated sepsis can be achieved by a novel form of trained innate …

Vulvovaginal candidiasis (VVC) affects nearly 3/4 of women during their lifetime, and its
symptoms seriously reduce quality of life. Although Candida albicans is a common …

Interactions between host and bacterial cells are integral to human physiology. The
complexity of host–microbe interactions extends to different cell types, spatial aspects, and …

In this issue of Cell Host & Microbe, Basso et al. delineate a mechanism for the fungal lipase
Lip2 during systemic infection with Candida albicans, the most common human fungal …

Chronic kidney disease (CKD) has historically been a significant global health concern,
profoundly impacting both life and well-being. In the process of CKD, with the gradual loss of …