Calmodulin (CaM) is a ubiquitous Ca 2+ receptor protein mediating a large number of
signaling processes in all eukaryotic cells. CaM plays a central role in regulating a myriad of …

Cryptococcosis is an infectious disease caused by pathogenic encapsulated yeasts in the
genus Cryptococcus. Currently, two species of these fungi commonly cause disease in …

Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

The number of immunocompromised patients with invasive fungal infections continues to
increase and new antifungal therapies are not keeping pace with the growing incidence of …

In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …

Iron overload is known to exacerbate many infectious diseases, and conversely, iron
withholding is an important defense strategy for mammalian hosts. Iron is a critical cue for …

Fungal meningitis is a serious disease caused by a fungal infection of the central nervous
system (CNS) mostly in individuals with immune system deficiencies. Fungal meningitis is …

Efficient communication with the environment is critical for all living organisms. Fungi utilize
complex signalling systems to sense their environments and control proliferation …

The implementation of Agrobacterium tumefaciens as a transformation tool revolutionized
approaches to discover and understand gene functions in a large number of fungal species …

Cryptococcus neoformans and Cryptococcus gattii are the cause of life-threatening
meningoencephalitis in immunocompromised and immunocompetent individuals …