Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Schiff base metal complexes as a versatile catalyst: A review

VK Juyal, A Pathak, M Panwar, SC Thakuri… - Journal of …, 2023 - Elsevier
This review presents the catalytic application of Schiff Base in different chemical reactions.
Schiff base ligands consist of imine (-C= N-) functional group derived from the condensation …

Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs

W Liu, R Gust - Chemical Society Reviews, 2013 - pubs.rsc.org
The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

Copper in diseases and treatments, and copper‐based anticancer strategies

F Tisato, C Marzano, M Porchia… - Medicinal research …, 2010 - Wiley Online Library
Copper is found in all living organisms and is a crucial trace element in redox chemistry,
growth and development. It is important for the function of several enzymes and proteins …

Green synthesis, characterization, antimicrobial and anticancer screening of new metal complexes incorporating Schiff base

AM Hassan, AO Said, BH Heakal, A Younis… - ACS …, 2022 - ACS Publications
A Schiff base ligand of o-vanillin and 4-aminoazobenzene and its transition metal
complexes of Ni (II), Co (II), Zn (II), Cu (II), Mn (II), and Zr (IV) were prepared under …

Manganese in health and disease

DS Avila, RL Puntel, M Aschner - … between essential metal ions and human …, 2013 - Springer
Manganese is an important metal for human health, being absolutely necessary for
development, metabolism, and the antioxidant system. Nevertheless, excessive exposure or …

DNA-binding of nickel (II), copper (II) and zinc (II) complexes: Structure–affinity relationships

G Barone, A Terenzi, A Lauria, AM Almerico… - Coordination Chemistry …, 2013 - Elsevier
Abstract Nickel (II), copper (II) and zinc (II) complexes with the same ligands normally display
analogous coordination geometry and binding mode toward DNA. However, although …

A Perspective–can copper complexes be developed as a novel class of therapeutics?

M Wehbe, AWY Leung, MJ Abrams, C Orvig… - Dalton …, 2017 - pubs.rsc.org
Although copper–ligand complexes appear to be promising as a new class of therapeutics,
other than the family of copper (II) coordination compounds referred to as casiopeínas these …

Anticancer potency of copper (II) complexes of thiosemicarbazones

NK Singh, AA Kumbhar, YR Pokharel… - Journal of Inorganic …, 2020 - Elsevier
Being a structural and catalytic cofactor in a number of biological pathways, copper
accumulates in tumors owing to selective permeability of the cancer cell membranes …

Biochemical pathways of copper complexes: Progress over the past 5 years

S Zehra, S Tabassum, F Arjmand - Drug Discovery Today, 2021 - Elsevier
Highlights•Overview of copper complexes as potent anticancer chemotherapeutic
agents.•Copper complexes are endogenously biocompatible and exhibit reduced side …