Identification of sensitive and specific biomarkers for early detection and prognosis of
prostate cancer is essential for timely and appropriate treatment of the disease in individual …

Cancer continues to be a major cause of mortality despite decades of effort and expense.
The problem reviewed here is that before many cancers are discovered they have already …

Patients presenting with metastatic adenocarcinoma of unknown origin are a common
clinical problem. Their optimal management and therapy are facilitated by identification of …

Abstract The 200-amino-acid repeat (HIN-200) gene family with the hematopoietic interferon
(IFN)-inducible nuclear protein encodes highly homologous proteins involved in cell growth …

Even the first expression profiling studies of breast cancers have generated new insights.
They suggest for example, that information about tumor aggressiveness, prognosis …

Breast cancer remains a leading cause of cancer death in women despite widespread
screening, in part because screening mammography has high rates of false-negative results …

Purpose: To provide practical considerations for diagnosing, counseling, and managing
patients at high risk for hereditary breast cancer. Design: We have studied 98 extended …

Introduction 3. MDM2 is potentially oncogenic 3.1. MDM2 overexpresses in tumor cells 3.2.
Amplification of mdm2 gene enhances tumorigenic potential of murine cells 3.3. Targeted …

The reliable detection of circulating tumor cells (CTCs) in metastatic breast cancer (MBC) is
possible by using immunomagnetic separation and subsequent characterization with the …

As the presence of tumor cells circulating in the blood is associated with systemic disease
and shortened survival, the establishment of a method to detect circulating tumor cells …