[HTML][HTML] Microarray-based identification and RT-PCR test screening for epithelial-specific mRNAs in peripheral blood of patients with colon cancer
Background The efficacy of screening for colorectal cancer using a simple blood-based
assay for the detection of tumor cells disseminated in the circulation at an early stage of the …
assay for the detection of tumor cells disseminated in the circulation at an early stage of the …
The growth arrest function of the human oncoprotein mouse double minute-2 is disabled by downstream mutation in cancer cells
R Zhou, R Frum, S Deb, SP Deb - Cancer research, 2005 - AACR
We have reported earlier that ectopic expression of mouse double minute-2 (MDM2)
induces G1 arrest in normal cells. To explain occasional overexpression of MDM2 in cancer …
induces G1 arrest in normal cells. To explain occasional overexpression of MDM2 in cancer …
Technical aspects of minimal residual disease detection in carcinoma patients
J Lacroix… - Seminars in surgical …, 2001 - Wiley Online Library
The burden of occult malignant cells which remains after a course of treatment that has
resulted in clinical remission is referred to as minimal residual disease (MRD). MRD is …
resulted in clinical remission is referred to as minimal residual disease (MRD). MRD is …
Recent advances in breast cancer biology
SM Domchek, BL Weber - Current opinion in oncology, 2002 - journals.lww.com
Developments in breast cancer biology over the last year have brought molecular medicine
closer to the clinic. Within the past year, two major advances have taken place. First …
closer to the clinic. Within the past year, two major advances have taken place. First …
The role of circulating tumor cells in breast cancer diagnosis and prediction of therapy response
JM Reuben, S Krishnamurthy… - Expert opinion on …, 2008 - Taylor & Francis
Background: Metastatic breast cancer (MBC) is incurable and any treatment is considered
palliative. Occult dissemination of tumor cells is responsible for recurrent MBC in patients …
palliative. Occult dissemination of tumor cells is responsible for recurrent MBC in patients …
[HTML][HTML] Regulation, restriction, and reminiscences
AB Pardee - Journal of Biological Chemistry, 2002 - ASBMB
I first thought about metabolic regulation while I was a postdoctoral fellow. We demonstrated
that oxalacetate inhibits succinic dehydrogenase, several steps back in the Krebs cycle (4). I …
that oxalacetate inhibits succinic dehydrogenase, several steps back in the Krebs cycle (4). I …
Interrelated two-way clustering and its application on gene expression data
C Tang, A Zhang - International Journal on Artificial Intelligence …, 2005 - World Scientific
Microarray technologies are capable of simultaneously measuring the signals for thousands
of messenger RNAs and large numbers of proteins from single samples. Arrays are now …
of messenger RNAs and large numbers of proteins from single samples. Arrays are now …
[HTML][HTML] Dichotomy in Hedgehog signaling between human healthy vessel and atherosclerotic plaques
The major cause for plaque instability in atherosclerotic disease is neoangiogenic
revascularization, but the factors controlling this process remain only partly understood …
revascularization, but the factors controlling this process remain only partly understood …
Loss of heterozygosity in serial plasma DNA samples during follow‐up of women with breast cancer
Q Wang, PS Larson, BL Schlechter… - … journal of cancer, 2003 - Wiley Online Library
We evaluated the potential utility of occult circulating tumor DNA as a molecular marker of
disease in subjects previously diagnosed with breast cancer. Using 24 microsatellite …
disease in subjects previously diagnosed with breast cancer. Using 24 microsatellite …
[HTML][HTML] Comparison of gene expression profile between blood cells and white adipose tissue of patients with obesity
MAS Pinhel, NY Noronha, CF Nicoletti… - … : Organo oficial de la …, 2017 - dialnet.unirioja.es
Objetivo: el objetivo de este estudio fue comparar, en individuos con obesidad, la expresión
de genes que regulan los procesos de adipogénesis (PLIN1, ADRB3 y PPARg2) y el …
de genes que regulan los procesos de adipogénesis (PLIN1, ADRB3 y PPARg2) y el …