The treatment of advanced thyroid cancer has undergone rapid evolution in the last decade,
with multiple kinase inhibitor drug approvals for each subtype of thyroid cancer and a …

Simple Summary Anaplastic thyroid carcinoma (ATC) has a dismal prognostic.
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …

Objective: To develop evidence-based recommendations for safe, effective, and appropriate
thyroidectomy. Background: Surgical management of thyroid disease has evolved …

Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …

The deadliest anaplastic thyroid cancer (ATC) often transforms from indolent differentiated
thyroid cancer (DTC); however, the complex intratumor transformation process is poorly …

Anaplastic thyroid cancer (ATC) and advanced differentiated thyroid cancers (DTCs) show
fatal outcomes, unlike DTCs. Here, we demonstrate mutational landscape of 27 ATCs and …

Background: Cancer stem cells (CSCs) are highly tumorigenic, chemotherapy-resistant,
tumor growth-sustaining, and are implicated in tumor recurrence. Previous studies have …

Purpose: Fibroblast activation protein (FAP) is a promising target for tumor treatment. In this
study, we aimed to investigate the safety and efficacy of the albumin binder-conjugated FAP …

Vitamin C is an antioxidant that may scavenge reactive oxygen species preventing DNA
damage and other effects important in cancer transformation. Dietary vitamin C from natural …

Background: Thyroid carcinoma is the most common malignant endocrine tumor; the
anaplastic thyroid cancer subtype is aggressive and has a poor prognosis. However, there is …