Improvement effect of metformin on female and male reproduction in endocrine pathologies and its mechanisms
AO Shpakov - Pharmaceuticals, 2021 - mdpi.com
Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …
combination with other drugs, restores the ovarian function in women with polycystic ovary …
Metformin in reproductive biology
M Faure, MJ Bertoldo, R Khoueiry… - Frontiers in …, 2018 - frontiersin.org
Initially produced in Europe in 1958, metformin is still one of the most widely prescribed
drugs to treat type II diabetes and other comorbidities associated with insulin resistance …
drugs to treat type II diabetes and other comorbidities associated with insulin resistance …
Chitosan-stabilized selenium nanoparticles and metformin synergistically rescue testicular oxidative damage and steroidogenesis-related genes dysregulation in high …
YM Abd El-Hakim, A Abdel-Rahman Mohamed… - Antioxidants, 2020 - mdpi.com
Background: this study examined the metformin (MF) and/or chitosan stabilized selenium
nanoparticles (CH-SeNPs) efficacy to alleviate the male reproductive function impairment in …
nanoparticles (CH-SeNPs) efficacy to alleviate the male reproductive function impairment in …
Roles of AMP-activated protein kinase (AMPK) in mammalian reproduction
W Yang, L Wang, F Wang, S Yuan - Frontiers in Cell and …, 2020 - frontiersin.org
Reproduction is an energy demanding function and only take place in case of sufficient
available energy status in mammals. Metabolic diseases such as anorexia nervosa are …
available energy status in mammals. Metabolic diseases such as anorexia nervosa are …
AMPK function in mammalian spermatozoa
D Martin-Hidalgo, A Hurtado de Llera… - International journal of …, 2018 - mdpi.com
AMP-activated protein kinase AMPK regulates cellular energy by controlling metabolism
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …
AMPK: a master energy regulator for gonadal function
From C. elegans to mammals (including humans), nutrition and energy metabolism
significantly influence reproduction. At the cellular level, some detectors of energy status …
significantly influence reproduction. At the cellular level, some detectors of energy status …
[HTML][HTML] Improving the post-thaw quality of rooster semen using the extender supplemented with resveratrol
FS Rezaie, M Hezavehei, M Sharafi, A Shahverdi - Poultry science, 2021 - Elsevier
Avian spermatozoa are highly susceptible to reactive oxygen species (ROS) produced
during the cryopreservation. The aim of the current study was to investigate the antioxidant …
during the cryopreservation. The aim of the current study was to investigate the antioxidant …
Odorant and taste receptors in sperm chemotaxis and cryopreservation: roles and implications in sperm capacitation, motility and fertility
MA Ali, Y Wang, Z Qin, X Yuan, Y Zhang, C Zeng - Genes, 2021 - mdpi.com
Sperm chemotaxis, which guide sperm toward oocyte, is tightly associated with sperm
capacitation, motility, and fertility. However, the molecular mechanism of sperm chemotaxis …
capacitation, motility, and fertility. However, the molecular mechanism of sperm chemotaxis …
Nutritional signals and reproduction
There is extensive evidence that nutrition influences reproductive function in various
mammalian species (agricultural animals, rodents and human). However, the mechanisms …
mammalian species (agricultural animals, rodents and human). However, the mechanisms …
Central role of 5′-AMP-activated protein kinase in chicken sperm functions
TMD Nguyen, S Alves, I Grasseau… - Biology of …, 2014 - academic.oup.com
Avian gametes present specific features related to their internal long-term mode of
fertilization. Among other central actors of energetic metabolism control, it has been …
fertilization. Among other central actors of energetic metabolism control, it has been …