Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic, relapsing immune-mediated disease with a varying and sometimes severe disease …

Prevalence of symptoms of anxiety and depression in patients with inflammatory bowel disease: a systematic review and meta-analysis

B Barberio, M Zamani, CJ Black… - The Lancet …, 2021 - thelancet.com
Background Inflammatory bowel disease (IBD) is a lifelong condition with no cure. Patients
with IBD might experience symptoms of common mental disorders such as anxiety and …

Comorbid depression in medical diseases

SM Gold, O Köhler-Forsberg, R Moss-Morris… - Nature Reviews …, 2020 - nature.com
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

Identification of a choroid plexus vascular barrier closing during intestinal inflammation

S Carloni, A Bertocchi, S Mancinelli, M Bellini, M Erreni… - Science, 2021 - science.org
Up to 40% of patients with inflammatory bowel disease present with psychosocial
disturbances. We previously identified a gut vascular barrier that controls the dissemination …

Management of Crohn disease: a review

K Cushing, PDR Higgins - Jama, 2021 - jamanetwork.com
Importance Crohn disease, a chronic gastrointestinal inflammatory disease, is increasing in
incidence and prevalence in many parts of the world. Uncontrolled inflammation leads to …

Prevalence of irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease in remission: a systematic review and meta-analysis

KM Fairbrass, SJ Costantino, DJ Gracie… - The lancet …, 2020 - thelancet.com
Background Patients with inflammatory bowel disease (IBD) often report symptoms
compatible with irritable bowel syndrome (IBS), which might have an effect on psychological …

[HTML][HTML] Tryptophan-kynurenine metabolism: a link between the gut and brain for depression in inflammatory bowel disease

LM Chen, CH Bao, Y Wu, SH Liang, D Wang… - Journal of …, 2021 - Springer
Inflammatory bowel disease (IBD), which mainly includes ulcerative colitis (UC) and Crohn's
disease (CD), is a group of chronic bowel diseases that are characterized by abdominal …

The influence of the brain–gut axis in inflammatory bowel disease and possible implications for treatment

DJ Gracie, PJ Hamlin, AC Ford - The lancet Gastroenterology & …, 2019 - thelancet.com
Brain–gut interactions affect psychological wellbeing and symptom reporting in functional
gastrointestinal disorders; the presence of anxiety or depression is associated with the …

Guts and gall: bile acids in regulation of intestinal epithelial function in health and disease

P Hegyi, J Maléth, JR Walters… - Physiological …, 2018 - journals.physiology.org
Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …

[HTML][HTML] Stress triggers flare of inflammatory bowel disease in children and adults

Y Sun, L Li, R Xie, B Wang, K Jiang, H Cao - Frontiers in pediatrics, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease characterized by
chronic and relapsing manifestations. It is noteworthy that the prevalence of IBD is gradually …