Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents
Natural products represents an important source of new lead compounds in drug discovery
research. Several drugs currently used as therapeutic agents have been developed from …
research. Several drugs currently used as therapeutic agents have been developed from …
Nanotechnologies in food science: applications, recent trends, and future perspectives
Nanotechnology is a key advanced technology enabling contribution, development, and
sustainable impact on food, medicine, and agriculture sectors. Nanomaterials have potential …
sustainable impact on food, medicine, and agriculture sectors. Nanomaterials have potential …
Status and challenges of plant-anticancer compounds in cancer treatment
Nowadays, cancer is one of the deadliest diseases in the world, which has been estimated
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …
to cause 9.9 million deaths in 2020. Conventional treatments for cancer commonly involve …
[HTML][HTML] Podophyllotoxin and its derivatives: Potential anticancer agents of natural origin in cancer chemotherapy
S Motyka, K Jafernik, H Ekiert, J Sharifi-Rad… - Biomedicine & …, 2023 - Elsevier
The use of plant secondary metabolites has gained considerable attention among clinicians
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …
in the prevention and treatment of cancer. A secondary metabolite isolated mainly from the …
Nitrogen-containing heterocycles as anticancer agents: An overview
Background: Cancer is spreading all over the world, and it is becoming the leading cause of
major deaths. Today's most difficult task for every researcher is to invent a new drug that can …
major deaths. Today's most difficult task for every researcher is to invent a new drug that can …
Podophyllotoxin: history, recent advances and future prospects
Podophyllotoxin, along with its various derivatives and congeners are widely recognized as
broad-spectrum pharmacologically active compounds. Etoposide, for instance, is the …
broad-spectrum pharmacologically active compounds. Etoposide, for instance, is the …
Pharmacological potential of fungal endophytes associated with medicinal plants: A review
BS Adeleke, OO Babalola - Journal of Fungi, 2021 - mdpi.com
Endophytic microbes are microorganisms that colonize the intracellular spaces within the
plant tissues without exerting any adverse or pathological effects. Currently, the world …
plant tissues without exerting any adverse or pathological effects. Currently, the world …
Lactones: Classification, synthesis, biological activities, and industrial applications
SK Sartori, MAN Diaz, G Diaz-Muñoz - Tetrahedron, 2021 - Elsevier
This review summarizes the current knowledge on lactones, a class of biologically active
natural products isolated from a wide range of living organisms. Butenolide, 5, 6 …
natural products isolated from a wide range of living organisms. Butenolide, 5, 6 …
Plant associated fungal endophytes as a source of natural bioactive compounds
Endophytes are a potent source of bioactive compounds that mimic plant-based metabolites.
The relationship of host plant and endophyte is significantly associated with alteration in …
The relationship of host plant and endophyte is significantly associated with alteration in …
A comprehensive review of topoisomerase inhibitors as anticancer agents in the past decade
X Liang, Q Wu, S Luan, Z Yin, C He, L Yin, Y Zou… - European journal of …, 2019 - Elsevier
The topoisomerase enzymes play an important role in DNA metabolism, and searching for
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …