Photoacoustic imaging and photothermal therapy of semiconducting polymer nanoparticles: signal amplification and second near‐infrared construction

X Zhen, K Pu, X Jiang - Small, 2021 - Wiley Online Library
Photoacoustic (PA) imaging and photothermal therapy (PTT) have attracted extensive
attention in disease diagnosis and treatment. Although many exogenous contrast agents …

Biocatalytic nanomaterials: A new pathway for bacterial disinfection

X Fan, F Yang, C Nie, L Ma, C Cheng… - Advanced …, 2021 - Wiley Online Library
Clinical treatment of pathogenic infection has emerged as a growing challenge in global
public health. Such treatment is currently limited to antibiotics, but abuse of antibiotics have …

Reprogramming the Tumor Microenvironment through Second‐Near‐Infrared‐Window Photothermal Genome Editing of PD‐L1 Mediated by Supramolecular Gold …

H Tang, X Xu, Y Chen, H Xin, T Wan, B Li… - Advanced …, 2021 - Wiley Online Library
A photothermal genome‐editing strategy is described to improve immune checkpoint
blockade (ICB) therapy by CRISPR/Cas9‐mediated disruption of PD‐L1 and mild …

A polymer multicellular nanoengager for synergistic NIR‐II photothermal immunotherapy

C Xu, Y Jiang, Y Han, K Pu, R Zhang - Advanced Materials, 2021 - Wiley Online Library
Cell‐membrane‐coated nanoparticles (CCNPs) that integrate the biophysiological
advantages of cell membranes with the multifunctionalities of synthetic materials hold great …

Oxygen self-generating nanoreactor mediated ferroptosis activation and immunotherapy in triple-negative breast cancer

K Li, K Xu, Y He, Y Yang, M Tan, Y Mao, Y Zou… - ACS …, 2023 - ACS Publications
The hypoxia microenvironment of solid tumors poses a technological bottleneck for
ferroptosis and immunotherapy in clinical oncology. Nanoreactors based on special …

J‐Aggregation Strategy toward Potentiated NIR‐II Fluorescence Bioimaging of Molecular Fluorophores

X Hu, C Zhu, F Sun, Z Chen, J Zou, X Chen… - Advanced …, 2024 - Wiley Online Library
Molecular fluorophores emitting in the second near‐infrared (NIR‐II, 1000–1700 nm)
window with strong optical harvesting and high quantum yields hold great potential for in …

Catalytically Active CoFe2O4 Nanoflowers for Augmented Sonodynamic and Chemodynamic Combination Therapy with Elicitation of Robust Immune Response

S Fu, R Yang, J Ren, J Liu, L Zhang, Z Xu, Y Kang… - Acs Nano, 2021 - ACS Publications
A hypoxic and acidic tumor microenvironment (TME) plays a significant role in cancer
development through complex cellular signaling networks, and it is thus challenging to …

Second near‐infrared light‐activatable polymeric nanoantagonist for photothermal immunometabolic cancer therapy

C Xu, Y Jiang, J Huang, J Huang, K Pu - Advanced Materials, 2021 - Wiley Online Library
Immunometabolic modulation offers new opportunities to treat cancers as it is highly
associated with cancer progression and immunosuppressive microenvironment. However …

Leveraging semiconducting polymer nanoparticles for combination cancer immunotherapy

J Wu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Cancer immunotherapy has become a promising method for cancer treatment, bringing
hope to advanced cancer patients. However, immune‐related adverse events caused by …

Complementing cancer photodynamic therapy with ferroptosis through iron oxide loaded porphyrin-grafted lipid nanoparticles

X Liang, M Chen, P Bhattarai, S Hameed, Y Tang… - ACS …, 2021 - ACS Publications
Nanomaterials that combine multimodality imaging and therapeutic functions within a single
nanoplatform have drawn extensive attention for molecular medicines and biological …