Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …

[HTML][HTML] Microbiota dysbiosis in lung cancer: evidence of association and potential mechanisms

N Xu, L Wang, C Li, C Ding, C Li, W Fan… - Translational Lung …, 2020 - ncbi.nlm.nih.gov
Over the past decade, revolution in microbial research has provided valuable insights into
the function of microbes that inhabit human body. This complex community of microbes …

Immunotherapy for small cell lung cancer: mechanisms of resistance

G Hamilton, B Rath - Expert opinion on biological therapy, 2019 - Taylor & Francis
Introduction: Small cell lung cancer (SCLC) is a highly malignant disease with a dismal
prognosis that is currently being tested for theclinical activity of checkpoint inhibitors. SCLC …

Impact of COPD on prognosis of lung cancer: from a perspective on disease heterogeneity

W Wang, S Dou, W Dong, M Xie, L Cui… - … journal of chronic …, 2018 - Taylor & Francis
Background COPD is an important comorbidity of lung cancer, but the impact of COPD on
the outcomes of lung cancer remains uncertain. Because both COPD and lung cancer are …

The ubiquitin system: an emerging therapeutic target for lung cancer

JO Jin, N Puranik, QT Bui, D Yadav… - International journal of …, 2021 - mdpi.com
The ubiquitin system, present in all eukaryotes, contributes to regulating multiple types of
cellular protein processes such as cell signaling, cell cycle, and receptor trafficking, and it …

Spirometry performed as part of the Manchester community-based lung cancer screening programme detects a high prevalence of airflow obstruction in individuals …

H Balata, J Harvey, PV Barber, D Colligan, R Duerden… - Thorax, 2020 - thorax.bmj.com
Background COPD is a major cause of morbidity and mortality in populations eligible for
lung cancer screening. We investigated the role of spirometry in a community-based lung …

TWIST2 inhibits EMT and induces oxidative stress in lung cancer cells by regulating the FGF21-mediated AMPK/mTOR pathway

Y Song, W Zhang, J Zhang, Z You, T Hu, G Shao… - Experimental cell …, 2021 - Elsevier
Abstract Twist related protein 2 (TWIST2) plays an important role in bone development,
tumorigenesis, tumour progression and epithelial mesenchymal transition (EMT). At present …

Role of CD4+ T and CD8+ T Lymphocytes‐Mediated Cellular Immunity in Pathogenesis of Chronic Obstructive Pulmonary Disease

W Xue, J Ma, Y Li, C Xie - Journal of Immunology Research, 2022 - Wiley Online Library
This work was to explore the changes of T lymphocyte subsets in peripheral blood of
patients with acute exacerbation of chronic obstructive pulmonary disease …

Trade-offs in aging lung diseases: a review on shared but opposite genetic risk variants in idiopathic pulmonary fibrosis, lung cancer and chronic obstructive …

CHM van Moorsel - Current opinion in pulmonary medicine, 2018 - journals.lww.com
The overlap in risk genes in aging lung diseases provides evidence that processes
associated with FAM13A, DSP and TERT are important for healthy aging. The opposite …

The link between chronic obstructive pulmonary disease phenotypes and histological subtypes of lung cancer: a case–control study

W Wang, M Xie, S Dou, L Cui, C Zheng… - International journal of …, 2018 - Taylor & Francis
Background COPD is considered an independent risk factor for lung cancer. COPD and lung
cancer are both very heterogeneous diseases, and the study herein investigates the link …