Evidence implicating Eph receptor tyrosine kinases and their ephrin ligands (that together
make up the 'Eph system') in cancer development and progression has been accumulating …

Simple Summary Glioblastoma (GBM) is the most severe and aggressive form of primary
brain tumor with a poor prognosis. Currently, the treatment for GBM treatment involves …

Liver fibrosis represents a reversible stage of various chronic liver diseases that progresses
to cirrhosis. This condition is characterized by an imbalance between tissue damage and …

Colorectal cancer is one of the most common malignant tumors in the digestive system, and
its high incidence and metastasis rate make it a terrible killer that threatens human health. In …

Invasive growth of glioblastoma makes residual tumor unremovable by surgery and leads to
disease relapse. Temozolomide is widely used first-line chemotherapy drug to treat glioma …

Simple Summary Glioblastoma is the most prevalent cerebral cancer in adults without
proven therapy. Chimeric antigen receptor T cell treatment has demonstrated good clinical …

Breast cancer is the most frequently diagnosed malignancy and the leading cause of cancer‐
related deaths in women worldwide. Cancer‐associated fibroblasts (CAFs) are one of the …

Background Valtrate, a natural compound isolated from the root of Valeriana, exhibits
antitumor activity in many cancers through different mechanisms. However, its efficacy for …

Emerging data have suggested that single short peptides have limited success as a cancer
vaccine; however, extending the short peptides into longer multi-epitope peptides overcame …

Glioblastoma (GBM), the predominant and primary malignant intracranial tumor, poses a
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …