Protein complexes are one of the most important functional units for deriving biological
processes within the cell. Experimental methods have provided valuable data to infer protein …

Protein complexes are the fundamental units for many cellular processes. Identifying protein
complexes accurately is critical for understanding the functions and organizations of cells …

Complex diseases are caused by a combination of genetic and environmental factors.
Uncovering the molecular pathways through which genetic factors affect a phenotype is …

Background Most proteins form macromolecular complexes to perform their biological
functions. However, experimentally determined protein complex data, especially of those …

Clustering is ubiquitously applied in bioinformatics with hierarchical clustering and k-means
partitioning being the most popular methods. Numerous improvements of these two …

A protein-protein interaction (PPI) network is a biomolecule relationship network that plays
an important role in biological activities. Studies of functional modules in a PPI network …

Owing to the lack of a universal definition of communities, some semi-supervised community
detection approaches learn the concept of community structures from known communities …

The ability to identify and characterize not only the protein-protein interactions but also their
internal modular organization through network analysis is fundamental for understanding …

Background Rhubarb, as a traditional Chinese medicine, is the preferred drug for the
treatment of stagnation and constipation in clinical practice. It has been reported that …

The growing accessibility of large-scale protein interaction data demands extensive
research to understand cell organization and its functioning at the network level …