Human beta defensin-3 mediated activation of β-catenin during human respiratory syncytial virus infection: interaction of HBD3 with LDL receptor-related protein 5

SM Pokharel, I Mohanty, C Mariasoosai… - Frontiers in …, 2023 - frontiersin.org
Respiratory Syncytial Virus (RSV) is a non-segmented negative-sense RNA virus belonging
to the paramyxovirus family. RSV infects the respiratory tract to cause pneumonia and …

Glycosaminoglycan, Antimicrobial Defence Molecule and Cytokine Appearance in Tracheal Hyaline Cartilage of Healthy Humans

A Deņisova, M Pilmane, P Fedirko - Journal of Functional Morphology …, 2022 - mdpi.com
Hyaline cartilage is an important tracheal structure, yet little is known about its molecular
composition, complicating investigation of pathologies and replacement options. Our aim …

[HTML][HTML] Human beta-defensin 1 circulating level and gene polymorphism in non-segmental vitiligo Egyptian patients

AGA Farag, MAAM Shoeib, AS Sleem… - Anais brasileiros de …, 2023 - SciELO Brasil
Background: Vitiligo is an acquired depigmented skin disorder. It has a genetic and
autoimmune background. Human beta defensin-1 (HBD-1) plus its gene polymorphism were …

[HTML][HTML] CCR6 activation links innate immune responses to mucosa-associated lymphoid tissue lymphoma development

B Korona, D Korona, W Zhao, AC Wotherspoon… - …, 2022 - ncbi.nlm.nih.gov
The genesis of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue
(MALT) is driven by oncogenic co-operation among immunological stimulations and …

Urine proteomics as a non-invasive approach to monitor exertional rhabdomyolysis during military training

A Carneiro, J Macedo-da-Silva, VF Santiago… - Journal of …, 2022 - Elsevier
Exertional rhabdomyolysis (ERM), a condition often associated with strenuous exercise, a
common practice in the military activities, can be defined as the process of injury and rupture …

Biochemical Composition of Synovial Fluid in Health and Disease

RT Keenan - Synovial Fluid Analysis and The Evaluation of Patients …, 2022 - Springer
The biochemical composition of synovial fluid is made up of lubricants, proteins, and small
molecules working synergistically to protect the joint from impact, friction, and disease …

Evaluation of the multiple tissue factors in bone of primary osteoplasty and rhinoplasty in patients affected by cleft lip palate

D Buile, M Pilmane, I Akota - 2022 - digitum.um.es
Clefts of the lip and/or palate (CLP) are visible disruptions of standard facial structure. The
aim of our study was to determine a relative number and appearance of the tissue factors in …

Filipendula glaberrima Nakai extract inhibits the bacterial infection by induction of HBD2 and HBD3 expression, and reduction of the inflammatory activity

AT Nguyen, M Kim, YE Kim, H Kim… - Microbiology and …, 2023 - Wiley Online Library
Defensins and inflammation are innate immune barriers of the body against infectious
pathogens. Searching for a compound that can inhibit infectious diseases by affecting …

The recombinant defensin/HSA fusion protein that inhibits NF-κb associated with intensive macropinocytosis shows potent efficacy against pancreatic cancer

Y Du, X Wang, X Liu, Y Li, Q Miao, M Jiang… - Biochemical …, 2022 - Elsevier
KRAS mutation and NF-κB both play crucial role in pancreatic cancer; in addition, defensin,
the peptide mediator in innate immunity, can inhibit NF-κB. Assuming a strategy that targets …

Defensins: Therapeutic molecules with potential to treat SARS-CoV-2 infection

S Banu, R Nagaraj, MM Idris - Indian Journal of Medical Research, 2022 - journals.lww.com
SARS-CoV-2 is a single-stranded enveloped virus23. It has 79 per cent genome similarity to
SARS-CoV-1 and 50 per cent genome similarity to MERS-CoV. The SARS-CoV-2 virus …