Chitosan chemistry and pharmaceutical perspectives

MNVR Kumar, RAA Muzzarelli, C Muzzarelli… - Chemical …, 2004 - ACS Publications
In the chitin bibliography, a major reference is the book written by Richards in 1951
“primarily for entomologists and other invertebrate zoologists” but also, in the author's hope …

[HTML][HTML] Chitosan microspheres in novel drug delivery systems

A Mitra, B Dey - Indian journal of pharmaceutical sciences, 2011 - ncbi.nlm.nih.gov
The main aim in the drug therapy of any disease is to attain the desired therapeutic
concentration of the drug in plasma or at the site of action and maintain it for the entire …

Preparation, characterization and antibacterial activities of chitosan, N-trimethyl chitosan (TMC) and N-diethylmethyl chitosan (DEMC) nanoparticles loaded with …

AMM Sadeghi, FA Dorkoosh, MR Avadi… - International Journal of …, 2008 - Elsevier
TMC and DEMC, quaternized derivatives of chitosan, have been shown to have penetration
enhancement properties and able to open the tight junctions of the intestinal epithelia at …

An in vivo comparison of intestinal pH and bacteria as physiological trigger mechanisms for colonic targeting in man

EL McConnell, MD Short, AW Basit - Journal of Controlled Release, 2008 - Elsevier
Targeting the colon for site-specific oral delivery can exploit one of two main physiological
triggers; the intestinal pH changes or the increase in bacterial numbers in the distal gut. This …

Buccal films of prednisolone with enhanced bioavailability

R Kumria, AB Nair, G Goomber, S Gupta - Drug delivery, 2016 - Taylor & Francis
The conventional formulation of prednisolone is considered to be low in efficacy, primarily
on account of their failure in providing and maintaining effective therapeutic drug levels. This …

Calcium pectinate gel beads obtained from callus cultures pectins as promising systems for colon-targeted drug delivery

EA Günter, OV Popeyko - Carbohydrate polymers, 2016 - Elsevier
Low methyl-esterified pectins obtained from the cell walls of the campion (SV, SV> 300),
tansy (TV, TV> 300) and duckweed (LM, LM> 300) callus cultures and apple pectin (AP …

Film coatings for oral colon delivery

A Maroni, MD Del Curto, L Zema, A Foppoli… - International journal of …, 2013 - Elsevier
Oral colon delivery is pursued through a number of formulation strategies with the aim of
enabling effective and well-tolerated treatments for large bowel pathologies or enhancing …

Physicochemical and swelling properties of composite gel microparticles based on alginate and callus cultures pectins with low and high degrees of …

EA Günter, OV Popeyko, VS Belozerov… - International Journal of …, 2020 - Elsevier
Composite gel microparticles based on alginate and callus culture pectins with low and high
degrees of methylesterification or apple pectin were produced. By varying the chemical …

[PDF][PDF] Characterization of psyllium (Plantago ovata) polysaccharide and its uses

AR Madgulkar, MRP Rao, D Warrier - Polysaccharides, 2015 - researchgate.net
The Plantago is one of the genera in family Plantaginaceae, a large genus of herbs or sub-
herbs distributed mostly in the temperate region and a few in the tropics. Psyllium has been …

Development and evaluation of chitosan and chitosan derivative nanoparticles containing insulin for oral administration

J Hecq, F Siepmann, J Siepmann… - Drug development and …, 2015 - Taylor & Francis
Chitosan and chitosan derivative-based nanoparticles loaded with insulin were prepared by
self-assembly, via electrostatic interactions between the negatively charged drug and the …