[HTML][HTML] Role of neuroinflammation in autism spectrum disorder and the emergence of brain histaminergic system. Lessons also for BPSD?

N Eissa, A Sadeq, A Sasse, B Sadek - Frontiers in pharmacology, 2020 - frontiersin.org
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in
executive functioning and communication deficits with those described in several …

Psychedelic‐inspired approaches for treating neurodegenerative disorders

HN Saeger, DE Olson - Journal of neurochemistry, 2022 - Wiley Online Library
Psychedelics are increasingly being recognized for their potential to treat a wide range of
brain disorders including depression, post‐traumatic stress disorder (PTSD), and substance …

Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation

JC Lennon, SL Aita, VAD Bene, T Rhoads… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Although dementia prevalence differs by race, it remains unclear whether
cognition and neuropsychiatric symptom severity differ between Black and White individuals …

[HTML][HTML] The role of serotonin in declarative memory: A systematic review of animal and human research

R Coray, BB Quednow - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The serotonergic system is involved in diverse cognitive functions including memory. Of
particular importance to daily life are declarative memories that contain information about …

[HTML][HTML] Comparisons of neuroinflammation, microglial activation, and degeneration of the locus coeruleus-norepinephrine system in APP/PS1 and aging mice

S Cao, DW Fisher, G Rodriguez, T Yu… - Journal of …, 2021 - Springer
Background The role of microglia in Alzheimer's disease (AD) pathogenesis is becoming
increasingly important, as activation of these cell types likely contributes to both pathological …

Cornuside ameliorates cognitive impairments in scopolamine induced AD mice: Involvement of neurotransmitter and oxidative stress

ZX Wang, WW Lian, J He, XL He, YM Wang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Cornus officinalis Sieb. et Zucc., traditional
Chinese medicine, has been widely used in the treatment of dementia. Cornel iridoid …

Effect of masupirdine (SUVN‐502) on cognition in patients with moderate Alzheimer's disease: A randomized, double‐blind, phase 2, proof‐of‐concept study

R Nirogi, J Ieni, VK Goyal, J Ravula… - … Research & Clinical …, 2022 - Wiley Online Library
Introduction This study explored the efficacy and safety of a serotonin‐6 receptor antagonist,
masupirdine, as adjunct treatment in patients with moderate Alzheimer's disease (AD) …

Treadmill exercise ameliorates chronic REM sleep deprivation-induced anxiety-like behavior and cognitive impairment in C57BL/6J mice

F Tai, C Wang, X Deng, R Li, Z Guo, H Quan, S Li - Brain research bulletin, 2020 - Elsevier
Various sleep disorders have deleterious effects on mental and cognitive performance.
Exercise, as an alternative therapeutic strategy, exerts beneficial impacts on human health …

[HTML][HTML] Behavioral and psychological symptoms of dementia as a means of communication: considerations for reducing stigma and promoting person-centered care

A Warren - Frontiers in psychology, 2022 - frontiersin.org
Dementia has rapidly become a major global health crisis. As the aging population
continues to increase, the burden increases commensurately on both individual and societal …

[HTML][HTML] Potential pathways for circadian dysfunction and sundowning-related behavioral aggression in Alzheimer's disease and related dementias

WD Todd - Frontiers in neuroscience, 2020 - frontiersin.org
Patients with Alzheimer's disease (AD) and related dementias are commonly reported to
exhibit aggressive behavior and other emotional behavioral disturbances, which create a …