Alzheimer's disease (AD) is a progressive, complex, and multifactorial neurodegenerative
disorder, still without effective and stable therapeutic strategies. Currently, available …

Background The source of yokukansan (YKS) is thought to be Baoying‐Jinjiang
(Hoeikinkyōroku in Japanese) by Xue Ji. YKS was originally designed for children and …

Multifunctional ligands as an essential variant of polypharmacology are promising
candidates for the treatment of multi-factorial diseases like Alzheimer's disease. Based on …

Alzheimer's disease (AD) represents the principal cause of dementia among the elderly.
Great efforts have been established to understand the physiopathology of AD. Changes in …

Alzheimer's disease (AD) is usually manifested in patients with dementia, accompanied by
anxiety and other mental symptoms. Emerging evidence from humans indicates that people …

It has been previously postulated that blood neurotransmitters might affect risks of
neurodegenerative diseases. Here, a Mendelian Randomization (MR) study was conducted …

The aim of this study was to examine the effects of olfactory stimulation on both cognitive
and behavioral symptoms in neurodegenerative diseases. The criteria for selection of …

Background: Despite the burden on patients and caregivers, there are no approved
therapies for the neuropsychiatric symptoms of Alzheimer's disease (NPS-AD). This is likely …

The improvement of existing techniques and the development of new molecular imaging
methods are an exciting and rapidly developing field in clinical care and research of …

High consumption of industrialized food with high fat content is generally associated with
insulin resistance, which in turn causes memory impairment and cognitive decline …