Pharmacological effects of baicalin in lung diseases

D Wang, Y Li - Frontiers in Pharmacology, 2023 - frontiersin.org
The flavonoids baicalin and baicalein were discovered in the root of Scutellaria baicalensis
Georgi and are primarily used in traditional Chinese medicine, herbal supplements and …

Recent advances in natural small molecules as drug delivery systems

S Fu, X Yang - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Drug delivery systems (DDSs) are a multidisciplinary approach toward the effective delivery
of drugs to their target sites. Natural small molecule (NSM) compounds with anticancer …

The role of IL-33/ST2 in COPD and its future as an antibody therapy

L Riera-Martínez, L Cànaves-Gómez, A Iglesias… - International journal of …, 2023 - mdpi.com
COPD is a leading cause of mortality and morbidity worldwide and is associated with a high
socioeconomic burden. Current treatment includes the use of inhaled corticosteroids and …

Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives

Y Zhou, Z Xu, Z Liu - Journal of Translational Medicine, 2023 - Springer
Abstract Interleukin (IL)-33 is an alarmin of the IL-1 superfamily localized to the nucleus of
expressing cells, such as endothelial cells, epithelial cells, and fibroblasts. In response to …

Association of dietary flavonoid intakes with prevalence of chronic respiratory diseases in adults

R Wu, X Zhu, G Guan, Q Cui, L Zhu, Y Xing… - Journal of Translational …, 2024 - Springer
Background and aims Flavonoids are a class of secondary plant metabolites that have been
shown to have multiple health benefits, including antioxidant and anti-inflammatory. This …

Luteolin alleviates oxidative stress in chronic obstructive pulmonary disease induced by cigarette smoke via modulation of the TRPV1 and CYP2A13/NRF2 signaling …

L Zhou, T Jian, Y Wan, R Huang, H Fang… - International Journal of …, 2023 - mdpi.com
The current study aims to investigate the therapeutic potential of luteolin (Lut), a naturally
occurring flavonoid found in various medicinal plants, for treating chronic obstructive …

Olea europaea L. Leaf Extract Alleviates Fibrosis Progression and Oxidative Stress Induced by Bleomycin on a Murine Model of Lung Fibrosis

S Bahri, A Abidi, A Nahdi, R Abdennabi… - Dose …, 2023 - journals.sagepub.com
In this study, we aim to investigate the effect of industrial Olea europaea L. leaf extract (OLE)
against bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats. Male Wistar rats were …

Generation of rat-derived lung epithelial cells in Fgfr2b-deficient mice retains species-specific development

S Yuri, Y Murase, A Isotani - Development, 2024 - journals.biologists.com
Regenerative medicine is a tool to compensate for the shortage of lungs for transplantation,
but it remains difficult to construct a lung in vitro due to the complex three-dimensional …

The utility of long non-coding RNAs in chronic obstructive pulmonary disease: a comprehensive analysis

Q Lin, C Zhang, H Weng, Y Lin, Y Lin, Z Ruan - BMC Pulmonary Medicine, 2023 - Springer
Objectives Chronic obstructive pulmonary disease (COPD) is one of the main causes of
morbidity and mortality in the world. However, there are some patients who are not …

Pharmacokinetics and tissue distribution of bleomycin-induced idiopathic pulmonary fibrosis rats treated with cryptotanshinone

X He, Z Zhong, Q Wang, Z Jia, J Lu, J Chen… - Frontiers in …, 2023 - frontiersin.org
Introduction: Cryptotanshinone (CTS), a compound derived from the root of Salvia
miltiorrhiza, has been linked to various of diseases, particularly pulmonary fibrosis. In the …