[HTML][HTML] Molecular pathways of major depressive disorder converge on the synapse
GR Fries, VA Saldana, J Finnstein, T Rein - Molecular psychiatry, 2023 - nature.com
Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …
molecular etiology. Extensive studies at different molecular levels point to a high complexity …
[HTML][HTML] Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …
Gut microbial metabolites as multi-kingdom intermediates
KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …
metabolites. These metabolites exert their effects within the host as signalling molecules and …
[PDF][PDF] The bidirectional relationship of depression and inflammation: double trouble
Depression represents the number one cause of disability worldwide and is often fatal.
Inflammatory processes have been implicated in the pathophysiology of depression. It is …
Inflammatory processes have been implicated in the pathophysiology of depression. It is …
Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome
BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …
Diet and depression: exploring the biological mechanisms of action
The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …
role for healthy dietary patterns in depression onset and symptom management. To guide …
Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …
the pathogenesis of disease, has been identified over the past two decades. One of the …
[HTML][HTML] Integrated cytokine and metabolite analysis reveals immunometabolic reprogramming in COVID-19 patients with therapeutic implications
N Xiao, M Nie, H Pang, B Wang, J Hu, X Meng… - Nature …, 2021 - nature.com
Cytokine release syndrome (CRS) is a major cause of the multi-organ injury and fatal
outcome induced by SARS-CoV-2 infection in severe COVID-19 patients. Metabolism can …
outcome induced by SARS-CoV-2 infection in severe COVID-19 patients. Metabolism can …
[HTML][HTML] The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
[HTML][HTML] IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression
A Sadik, LFS Patterson, S Öztürk, SR Mohapatra… - Cell, 2020 - cell.com
Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor
malignancy and suppresses anti-tumor immunity. The context specificity of AHR target …
malignancy and suppresses anti-tumor immunity. The context specificity of AHR target …