[HTML][HTML] The roles of miRNA, lncRNA and circRNA in the development of osteoporosis

Y Yang, W Yujiao, W Fang, Y Linhui, G Ziqi… - Biological …, 2020 - SciELO Chile
Osteoporosis is a common metabolic bone disease, influenced by genetic and
environmental factors, that increases bone fragility and fracture risk and, therefore, has a …

Oxidative stress and inflammation in osteoporosis: molecular mechanisms involved and the relationship with microRNAs

T Iantomasi, C Romagnoli, G Palmini, S Donati… - International journal of …, 2023 - mdpi.com
Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …

miRNAs as potential game-changers in bone diseases: Future medicinal and clinical Uses

AS Doghish, MS Elballal, O Elazazy… - … -Research and Practice, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene
expression by sequential mechanisms such as mRNA breakdown or translational …

Functional relationship between osteogenesis and angiogenesis in tissue regeneration

F Diomede, GD Marconi, L Fonticoli… - International Journal of …, 2020 - mdpi.com
Bone tissue renewal can be outlined as a complicated mechanism centered on the
interaction between osteogenic and angiogenic events capable of leading to bone formation …

Exosomes derived from miR‐375‐overexpressing human adipose mesenchymal stem cells promote bone regeneration

S Chen, Y Tang, Y Liu, P Zhang, L Lv, X Zhang… - Cell …, 2019 - Wiley Online Library
Objectives The present study aimed to investigate whether exosomes derived from miR‐375‐
overexpressing human adipose mesenchymal stem cells (hASCs) could enhance bone …

Bone regeneration is mediated by macrophage extracellular vesicles

M Kang, CC Huang, Y Lu, S Shirazi, P Gajendrareddy… - Bone, 2020 - Elsevier
Multiple local and systemic factors including inflammation influence bone regeneration.
Several lines of evidence demonstrate that macrophages contribute to the immunological …

Dietary anti-aging polyphenols and potential mechanisms

J Luo, H Si, Z Jia, D Liu - Antioxidants, 2021 - mdpi.com
For years, the consumption of a diet rich in fruits and vegetables has been considered
healthy, increasing longevity, and decreasing morbidities. With the assistance of basic …

Extracellular signal-regulated kinase: a regulator of cell growth, inflammation, chondrocyte and bone cell receptor-mediated gene expression

N Lu, CJ Malemud - International journal of molecular sciences, 2019 - mdpi.com
Extracellular signal-regulated kinase (ERK) is a member of the mitogen-activated protein
kinase family of signaling molecules. ERK is predominantly found in two forms, ERK1 (p44) …

MicroRNAs as modulators of longevity and the aging process

HE Kinser, Z Pincus - Human genetics, 2020 - Springer
MicroRNAs (miRNAs) are short, non-coding RNAs that post-transcriptionally repress
translation or induce mRNA degradation of target transcripts through sequence-specific …

The role of miR‐29 family in disease

M Horita, C Farquharson… - Journal of cellular …, 2021 - Wiley Online Library
MicroRNAs are small noncoding RNAs that can bind to the target sites in the 3'‐untranslated
region of messenger RNA to regulate posttranscriptional gene expression. Increasing …