Pulmonary hypertension (PH) is a classic pathophysiological consequence of left-sided
valvular heart disease (VHD). However, as opposed to other forms of PH, there are relatively …

Invasive cardiopulmonary exercise testing (iCPET) combines full central hemodynamic
assessment with continuous measurements of pulmonary gas exchange and ventilation to …

Rationale: Exercise tolerance is decreased in patients with pulmonary hypertension (PH). It
is unknown whether exercise intolerance in PH coincides with an impaired rest-to-exercise …

Increased ventilation relative to metabolic demands, indicating alveolar hyperventilation
and/or increased physiological dead space (excess ventilation), is a key cause of exertional …

Pulmonary arterial hypertension (PAH) is a chronic disease with poor prognosis and
important exercise limitation despite the proliferation of treatment options in the last decade …

Pulmonary arterial hypertension (PAH) is characterized by a continuous increase in pre-
capillary pulmonary vascular resistance (PVR) with a progressive reduction of cardiac output …

Introduction: Exercise intolerance in pulmonary hypertension (PH) is a major factor affecting
activities of daily living and quality of life. Evaluation strategies (ie, non-invasive and …

Pulmonary arterial hypertension (PAH) is a rare and devastating disease characterized by
progressive increases in pulmonary arterial pressure and pulmonary vascular resistance …

Given the unique and clinically ominous pathology associated with pulmonary arterial (PA)
hypertension (PH) and its implications for the eventual deterioration of right ventricular …

Despite the progress made in recent years in diseasetargeted therapies and the
improvement in prognosis, patients with pulmonary arterial hypertension (PAH) often …