Much of biology is rhythmical and comprises oscillators that can couple. These have
optimized energy efficiency and have been preserved during evolution. The respiratory and …

The importance of chemoreflex function for cardiovascular health is increasingly recognized
in clinical practice. The physiological function of the chemoreflex is to constantly adjust …

Background: Central sleep apnea (CSA) is common among patients with heart failure and
has been strongly linked to adverse outcomes. However, progress toward improving …

Central sleep apnea (CSA) is characterized by intermittent repetitive cessation and/or
decreased breathing without effort. Specific precipitating mechanisms may vary, but it is …

Three decades ago, continuous positive airway pressure (CPAP) was introduced to treat
obstructive sleep apnea (OSA). Shortly after, bilevel positive airway pressure devices …

Purpose Guidelines recommend considering an initial trial of continuous positive airway
pressure (CPAP) to treat central sleep apnea (CSA). However, practice patterns vary widely …

Central sleep apnea (CSA) frequently coexists with heart failure and atrial fibrillation and
contributes to cardiovascular disease progression and mortality. A transvenous phrenic …

Background The response to cardiac resynchronization therapy (CRT) is suboptimal in one-
third of patients. Objectives The study aimed to evaluate the impact of sleep-disordered …

Study Objectives: Obstructive sleep apnea (OSA) often coexists with heart failure (HF) and is
commonly treated with positive airway pressure (PAP) therapy. Periodic breathing (PB) may …

The prevalence of central sleep apnea (CSA) is rare in general population. However, CSA is
prevalent in those with cardiovascular and cerebrovascular disorders. CSA may persist or …