Abstract Development of monoclonal antibodies (mAbs) and their functional derivatives
represents a growing segment of the development pipeline in the pharmaceutical industry …

Monoclonal antibodies (mAb) are emerging as one of the major class of therapeutic agents
in the treatment of many human diseases, in particular in cancer and immunological …

Purpose: CPX-1 is a novel, liposome-encapsulated formulation of irinotecan and floxuridine
designed to prolong in vitro optimized synergistic molar ratios of both drugs postinfusion …

Angiogenesis affects both wound healing and malignant cell growth through nutrients and
oxygen. Vascular endothelial growth factor (VEGF) is the most important element involved in …

Background Intra-arterial radioembolization with yttrium-90 microspheres (90 Y-RE) is an
increasingly used therapy for patients with unresectable liver malignancies. Over the last …

PURPOSE: Radiofrequency (RF) ablation is an increasingly accepted treatment for
nonsurgical candidates with a limited number of colorectal hepatic metastases. RF ablation …

Objective: The safety profiles of oral fluoropyrimidines were compared with 5-fluorouracil (5-
FU) using adverse event reports (AERs) submitted to the Adverse Event Reporting System …

Although metastatic colorectal cancer (mCRC) is commonly treated with 5-fluorouracil (5-
FU)/leucovorin/oxaliplatin (FOLFOX), their response to FOLFOX varies, and no biomarkers …

This systematic review evaluates the clinical evidence for the addition of herbal medicines
(HMs) to FOLFOX 4 for advanced colorectal cancer (ACRC) in terms of tumor response rate …

Purpose Biodegradable polylactic-co-glycolic acid (PLGA) nanoparticles can adsorb at the
water/oil interface to stabilize the emulsion (forming Pickering-emulsion). The purpose of this …