Tumor microenvironment complexity and therapeutic implications at a glance
R Baghban, L Roshangar… - Cell Communication and …, 2020 - Springer
The dynamic interactions of cancer cells with their microenvironment consisting of stromal
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …
cells (cellular part) and extracellular matrix (ECM) components (non-cellular) is essential to …
Novel nanomedicines to overcome cancer multidrug resistance
Z Su, S Dong, SC Zhao, K Liu, Y Tan, X Jiang… - Drug Resistance …, 2021 - Elsevier
Chemotherapy remains a powerful tool to eliminate malignant cells. However, the efficacy of
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …
chemotherapy is compromised by the frequent emergence of intrinsic and acquired …
Cancer stem cell (CSC) resistance drivers
M Najafi, K Mortezaee, J Majidpoor - Life sciences, 2019 - Elsevier
Cancer stem cells (CSCs) are a population of self-renewal cells with high tumorigenic
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …
Cancer stem cells (CSCs) in cancer progression and therapy
Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …
[HTML][HTML] Recent advances in drug delivery systems for targeting cancer stem cells
H Duan, Y Liu, Z Gao, W Huang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
Nano-based approved pharmaceuticals for cancer treatment: present and future challenges
F Rodríguez, P Caruana, N De la Fuente, P Español… - Biomolecules, 2022 - mdpi.com
Cancer is one of the main causes of death worldwide. To date, and despite the advances in
conventional treatment options, therapy in cancer is still far from optimal due to the non …
conventional treatment options, therapy in cancer is still far from optimal due to the non …
Triggered ferroptotic polymer micelles for reversing multidrug resistance to chemotherapy
M Gao, J Deng, F Liu, A Fan, Y Wang, H Wu, D Ding… - Biomaterials, 2019 - Elsevier
Drug-tolerant persister cancer cells (PCCs) play an important role in the development of
multidrug resistance (MDR) to anti-cancer drugs. This is due to the strong link between …
multidrug resistance (MDR) to anti-cancer drugs. This is due to the strong link between …
Horizontal gene transfer: from evolutionary flexibility to disease progression
M Emamalipour, K Seidi, S Zununi Vahed… - Frontiers in cell and …, 2020 - frontiersin.org
Flexibility in the exchange of genetic material takes place between different organisms of the
same or different species. This phenomenon is known to play a key role in the genetic …
same or different species. This phenomenon is known to play a key role in the genetic …
[HTML][HTML] Molecular targets, therapeutic agents and multitasking nanoparticles to deal with cancer stem cells: A narrative review
There is increasing evidence that malignant tumors are initiated and maintained by a sub-
population of tumor cells that have similar biological properties to normal adult stem cells …
population of tumor cells that have similar biological properties to normal adult stem cells …
Target based chemotherapeutic advancement of ruthenium complexes
BK Kundu, S Mukhopadhyay - Coordination Chemistry Reviews, 2021 - Elsevier
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …