CRISPR-Cas9-mediated gene therapy in neurological disorders
L Guan, Y Han, C Yang, S Lu, J Du, H Li, J Lin - Molecular Neurobiology, 2022 - Springer
Neurological disorders are primarily diseases with sophisticated etiology that are always
refractory and recrudescent. The major obstruction to effective therapies for neurological …
refractory and recrudescent. The major obstruction to effective therapies for neurological …
Polyglutamine (PolyQ) Diseases: Navigating the Landscape of Neurodegeneration
Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders
caused by expanded cytosine-adenine-guanine (CAG) repeats encoding proteins with …
caused by expanded cytosine-adenine-guanine (CAG) repeats encoding proteins with …
[HTML][HTML] Spinocerebellar ataxia type 31: A clinical and radiological literature review
J Saucier, M Al-Qadi, MB Amor, K Ishikawa… - Journal of the …, 2023 - Elsevier
Abstract Spinocerebellar ataxia type 31 (SCA31) is an autosomal dominant disease,
classified amongst pure cerebellar ataxias (ADCA type 3). While SCA31 is the third most …
classified amongst pure cerebellar ataxias (ADCA type 3). While SCA31 is the third most …
Development of CRISPR Cas9, spin-off technologies and their application in model construction and potential therapeutic methods of Parkinson's disease
J Qu, N Liu, L Gao, J Hu, M Sun, D Yu - Frontiers in Neuroscience, 2023 - frontiersin.org
Parkinson's disease (PD) is one of the most common degenerative diseases. It is most
typically characterized by neuronal death following the accumulation of Lewis inclusions in …
typically characterized by neuronal death following the accumulation of Lewis inclusions in …
Development of a Polymeric Pharmacological Nanocarrier System as a Potential Therapy for Spinocerebellar Ataxia Type 7
FV Borbolla-Jiménez, IA García-Aguirre… - Cells, 2023 - mdpi.com
Spinocerebellar ataxia type 7 (SCA7) is an autosomal-dominant inherited disease
characterized by progressive ataxia and retinal degeneration. SCA7 belongs to a group of …
characterized by progressive ataxia and retinal degeneration. SCA7 belongs to a group of …
Analysis and hierarchical clustering of infratentorial morphological MRI identifies SCAs phenogroups
J Zhao, W Zeng, X Huang, M Hu, K Yuan, C Wu… - Journal of …, 2023 - Springer
Background Clinical decision-making in spinocerebellar ataxia spectrum diseases (SCAs)
has mainly been based on genetic tests, not considering the SCAs' imaging and clinical …
has mainly been based on genetic tests, not considering the SCAs' imaging and clinical …
Genetic distribution of five spinocerebellar ataxia microsatellite loci in mexican native american populations and its impact on contemporary mestizo populations
Spinocerebellar ataxias (SCAs) conform a heterogeneous group of neurodegenerative
disorders with autosomal dominant inheritance. Five of the most frequent SCAs are caused …
disorders with autosomal dominant inheritance. Five of the most frequent SCAs are caused …
[PDF][PDF] DESCRIPCIÓN CLÍNICO-EPIDEMIOLÓGICA DE LA ATAXIA ESPINOCEREBELOSA TIPO 7 (SCA7) EN LA REGIÓN CENTRAL DE VERACRUZ, MÉXICO
LGI Ibarra - 2022 - ru.dgb.unam.mx
Las Ataxias Hereditarias (AH) abarcan un grupo heterogéneo de entidades genéticas que
clínicamente comparten marcha con amplia base de sustentación, incoordinación motriz …
clínicamente comparten marcha con amplia base de sustentación, incoordinación motriz …
[PDF][PDF] Genetic Distribution of Five Spinocerebellar Ataxia Microsatellite Loci in Mexican Native American Populations and Its Impact on Contemporary Mestizo …
Spinocerebellar ataxias (SCAs) conform a heterogeneous group of neurodegenerative
disorders with autosomal dominant inheritance. Five of the most frequent SCAs are caused …
disorders with autosomal dominant inheritance. Five of the most frequent SCAs are caused …