The molecular pathophysiology of depression and the new therapeutics
H Tian, Z Hu, J Xu, C Wang - MedComm, 2022 - Wiley Online Library
Major depressive disorder (MDD) is a highly prevalent and disabling disorder. Despite the
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …
many hypotheses proposed to understand the molecular pathophysiology of depression, it is …
[HTML][HTML] A microbial-based approach to mental health: the potential of probiotics in the treatment of depression
D Johnson, V Letchumanan, CC Thum… - Nutrients, 2023 - mdpi.com
Probiotics are currently the subject of intensive research pursuits and also represent a multi-
billion-dollar global industry given their vast potential to improve human health. In addition …
billion-dollar global industry given their vast potential to improve human health. In addition …
Role of inflammatory mechanisms in major depressive disorder: from etiology to potential pharmacological targets
BR Kouba, L de Araujo Borba, P Borges de Souza… - Cells, 2024 - mdpi.com
The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …
of major depressive disorder (MDD) has been demonstrated. The increase of pro …
[HTML][HTML] Depression pathophysiology: Astrocyte mitochondrial melatonergic pathway as crucial hub
G Anderson - International Journal of Molecular Sciences, 2022 - mdpi.com
Major depressive disorder (MDD) is widely accepted as having a heterogenous
pathophysiology involving a complex mixture of systemic and CNS processes. A …
pathophysiology involving a complex mixture of systemic and CNS processes. A …
[HTML][HTML] The current state of research for psychobiotics use in the management of psychiatric disorders–A systematic literature review
O Vasiliu - Frontiers in Psychiatry, 2023 - frontiersin.org
The need to find new therapeutic interventions in patients diagnosed with psychiatric
disorders is supported by the data suggesting high rates of relapse, chronic evolution …
disorders is supported by the data suggesting high rates of relapse, chronic evolution …
The role of dietary intake of live microbes in the association between leisure-time physical activity and depressive symptoms: A population-based study
Y You, R Wang, J Li, F Cao, Y Zhang… - Applied Physiology …, 2024 - cdnsciencepub.com
Current research has shown promising associations between factors such as diet, total
physical activity, and mental health outcomes, acknowledging the intricate interplay between …
physical activity, and mental health outcomes, acknowledging the intricate interplay between …
Potential of postbiotics for the treatment of metabolic disorders
Postbiotics, the next generation of probiotics, are extracts that are free of living and
nonviable bacteria and show strong modulatory effects on the gut flora. Examples include …
nonviable bacteria and show strong modulatory effects on the gut flora. Examples include …
Effect of Dendrobium officinale polysaccharides on central nervous system disease: Based on gut microbiota
L Xu, X Zeng, Y Liu, Z Wu, X Zheng, X Zhang - International Journal of …, 2023 - Elsevier
Dendrobium officinale has anti-inflammatory effects and is one of the well-known functional
foods. Dendrobium officinale polysaccharide (DOP) can reduce intestinal barrier disruption …
foods. Dendrobium officinale polysaccharide (DOP) can reduce intestinal barrier disruption …
[HTML][HTML] Biology of cyclooxygenase-2: An application in depression therapeutics
Y He, Y Han, X Liao, M Zou, Y Wang - Frontiers in Psychiatry, 2022 - frontiersin.org
Depressive Disorder is a common mood disorder or affective disorder that is dominated by
depressed mood. It is characterized by a high incidence and recurrence. The onset of …
depressed mood. It is characterized by a high incidence and recurrence. The onset of …
Targeting the gut–microbiota–brain axis in irritable bowel disease to improve cognitive function–recent knowledge and emerging therapeutic opportunities
H Tang, X Chen, S Huang, G Yin, X Wang… - Reviews in the …, 2023 - degruyter.com
The brain–gut axis forms a bidirectional communication system between the gastrointestinal
(GI) tract and cognitive brain areas. Disturbances to this system in disease states such as …
(GI) tract and cognitive brain areas. Disturbances to this system in disease states such as …