Dendritic spines are small, thin, specialized protrusions from neuronal dendrites, primarily
localized in the excitatory synapses. Sophisticated imaging techniques revealed that …

The protein brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family
of growth factors involved in plasticity of neurons in several brain regions. There are …

Sleep homeostasis is a complex neurobiologic phenomenon involving a number of
molecular pathways, neurotransmitter release, synaptic activity, and factors modulating …

Major depressive disorder is among the most commonly diagnosed disabling mental
diseases. Several non-pharmacological treatments of depression upregulate adenosine …

Eukaryotic elongation factor 2 kinase (eEF2K) is a member of the small group of atypical 'α-
kinases'. It phosphorylates and inhibits eukaryotic elongation factor 2, to slow down the …

It is commonly accepted that brain plasticity occurs in wakefulness and sleep. However, how
these different brain states work in concert to create long-lasting changes in brain circuitry is …

Arc (activity‐regulated cytoskeleton‐associated protein) is posited as a critical regulator of
long‐term synaptic plasticity at excitatory synapses, including long‐term potentiation, long …

Sleep deprivation is a public health epidemic that causes wide-ranging deleterious
consequences, including impaired memory and cognition. Protein synthesis in hippocampal …

The structure and dynamics of dendritic spines reflect the strength of synapses, which are
severely affected in different brain diseases. Therefore, understanding the ultra-structure …

Understanding the links between sleep and brain development is important, as rapid eye
movement (REM) sleep and non‐REM (NREM) sleep seem to contribute to different aspects …