[HTML][HTML] Protein-based nanoparticles as drug delivery systems
Nanoparticles have been extensively used as carriers for the delivery of chemicals and
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …
biomolecular drugs, such as anticancer drugs and therapeutic proteins. Natural …
Metabolomics in diabetes and diabetic complications: insights from epidemiological studies
Q Jin, RCW Ma - Cells, 2021 - mdpi.com
The increasing prevalence of diabetes and its complications, such as cardiovascular and
kidney disease, remains a huge burden globally. Identification of biomarkers for the …
kidney disease, remains a huge burden globally. Identification of biomarkers for the …
Antioxidant properties of anthocyanins and their mechanism of action in atherosclerosis
Atherosclerosis develops due to lipid accumulation in the arterial wall and sclerosis as result
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …
of increased hyperlipidemia, oxidative stress, lipid oxidation, and protein oxidation …
[HTML][HTML] COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches
AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The current coronavirus disease 2019 (COVID‐19) pandemic presents a global challenge
for managing acutely ill patients and complications from viral infection. Systemic …
for managing acutely ill patients and complications from viral infection. Systemic …
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality
Mendelian randomization (MR) is a burgeoning field that involves the use of genetic variants
to assess causal relationships between exposures and outcomes. MR studies can be …
to assess causal relationships between exposures and outcomes. MR studies can be …
Nanodiscs: a versatile nanocarrier platform for cancer diagnosis and treatment
J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
Effects of low-carbohydrate diets v. low-fat diets on body weight and cardiovascular risk factors: a meta-analysis of randomised controlled trials
N Mansoor, KJ Vinknes, MB Veierød… - British Journal of …, 2016 - cambridge.org
The effects of low-carbohydrate (LC) diets on body weight and cardiovascular risk are
unclear, and previous studies have found varying results. Our aim was to conduct a meta …
unclear, and previous studies have found varying results. Our aim was to conduct a meta …
RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and …
D Karunakaran, MA Nguyen, M Geoffrion, D Vreeken… - Circulation, 2021 - Am Heart Assoc
Background: Chronic activation of the innate immune system drives inflammation and
contributes directly to atherosclerosis. We previously showed that macrophages in the …
contributes directly to atherosclerosis. We previously showed that macrophages in the …
Elimination of established tumors with nanodisc-based combination chemoimmunotherapy
Although immune checkpoint blockade has shown initial success for various cancers, only a
small subset of patients benefits from this therapy. Some chemotherapeutic drugs have been …
small subset of patients benefits from this therapy. Some chemotherapeutic drugs have been …
HDL cholesterol: reappraisal of its clinical relevance
W März, ME Kleber, H Scharnagl, T Speer… - Clinical Research in …, 2017 - Springer
Background While several lines of evidence prove that elevated concentrations of low-
density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its …
density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its …