The concept of geroscience is that since ageing is the greatest risk factor for many diseases
and conditions, targeting the ageing process itself will have the greatest impact on human …

Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

Arming activatable mild-photothermal therapy (PTT) with the property of relieving tumor
thermotolerance holds great promise for overcoming traditional mild PTT limitations such as …

Maintaining a healthy proteome is fundamental for the survival of all organisms. Integral to
this are Hsp90 and Hsp70, molecular chaperones that together facilitate the folding …

Photothermal therapy (PTT), which utilizes near‐infrared light‐absorbing agents to ablate
tumor, has emerged as a highly promising anticancer strategy and received intensive …

Thermoelectric therapy has emerged as a promising treatment strategy for oncology, but it is
still limited by the low thermoelectric catalytic efficiency at human body temperature and the …

Hsp90 is a conserved and essential molecular chaperone responsible for the folding and
activation of hundreds of 'client'proteins,–. The glucocorticoid receptor (GR) is a model client …

Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

Drought stress is one of the most adverse abiotic stresses that hinder plants' growth and
productivity, threatening sustainable crop production. It impairs normal growth, disturbs …

Necroptosis and ferroptosis are two distinct necrotic cell death modalities with no known
common molecular mechanisms. Necroptosis is activated by ligands of death receptors such …