Breast cancer is a sporadic disease with genetic and epigenetic components. Genomic
instability in breast cancer leads to mutations, copy number variations, and genetic …

Simple Summary Maintenance of telomeres is a fundamental step in human carcinogenesis
and is primarily regulated by telomerase and the human telomerase reverse transcriptase …

Long noncoding RNAs (lncRNA) are dysregulated in various human cancers and control
tumor development and progression. However, the upstream mechanisms underlying their …

Recently, a large number of studies have shown that circular RNA (circRNA) is involved in
the development and progression of human cancer. However, its role in triple-negative …

Background Aberrant microRNA expression has been implicated in metastasis of cancers.
MiR-661 accelerates proliferation and invasion of breast cancer and ovarian cancer, while …

Increasing evidence demonstrates the crucial regulatory functions of circular RNAs in
different cancer types. The major aim of the current study was to establish functions of …

Abstract miR-152 and lncRNA H19 have been frequently implicated in various cellular
processes including cell proliferation, invasion, angiogenesis, and apoptosis. However, the …

Telomeres, protective DNA-protein complexes at the end of eukaryotic linear chromosomes,
play pivotal roles in the maintenance of genomic stability during cell division. When …

Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase
and plays important roles in human cancers. Aberrant expression of hTERT is closely …

Increasing evidence has indicated that long non-coding RNAs (LncRNAs) play multiple
functions in the development of cancer and function as indicators of diagnosis and …