The neuroscience of tinnitus

JJ Eggermont, LE Roberts - Trends in neurosciences, 2004 - cell.com
Tinnitus is an auditory phantom sensation (ringing of the ears) experienced when no
external sound is present. Most but not all cases are associated with hearing loss induced …

An integrative model of tinnitus based on a central gain controlling neural sensitivity

AJ Noreña - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
The purpose of the current review is to propose a model highlighting the putative
connections between hearing loss and the phantom perception of tinnitus (tinnitus being …

Beyond cochlear implants: awakening the deafened brain

DR Moore, RV Shannon - Nature neuroscience, 2009 - nature.com
Cochlear implants have provided hearing to more than 120,000 deaf people. Recent
surgical developments include direct electrical stimulation of the brain, bilateral implants and …

Hearing loss, hyperacusis, or tinnitus: what is modeled in animal research?

JJ Eggermont - Hearing research, 2013 - Elsevier
Animal models of tinnitus require a behavioral correlate thereof. Various conditioned
response methods and gap-startle reflex methods are in use and the outcomes generally …

New criteria of indication and selection of patients to cochlear implant

ALL Sampaio, MFS Araújo… - International journal of …, 2011 - Wiley Online Library
Numerous changes continue to occur in cochlear implant candidacy. In general, these have
been accompanied by concomitant and satisfactory changes in surgical techniques …

Ototoxicity: mechanisms of cochlear impairment and its prevention

K Tabuchi, B Nishimura, M Nakamagoe… - Current medicinal …, 2011 - ingentaconnect.com
Aminoglycosides, cisplatin, and non-steroidal anti-inflammatory drugs (NSAIDs) are widely
used pharmacological agents. There is a possibility, however, that the use of these agents …

Tinnitus correlates with downregulation of cortical glutamate decarboxylase 65 expression but not auditory cortical map reorganization

A Miyakawa, W Wang, SJ Cho, D Li… - Journal of …, 2019 - Soc Neuroscience
Hearing loss is the biggest risk factor for tinnitus, and hearing-loss-related pathological
changes in the auditory pathway have been hypothesized as the mechanism underlying …

Neural changes in the auditory cortex of awake guinea pigs after two tinnitus inducers: salicylate and acoustic trauma

AJ Norena, G Moffat, JL Blanc, L Pezard, Y Cazals - Neuroscience, 2010 - Elsevier
Tinnitus, also called phantom auditory perception, is a major health problem in western
countries. As such, a significant amount of effort has been devoted to understanding its …

Salicylate-induced peripheral auditory changes and tonotopic reorganization of auditory cortex

D Stolzberg, GD Chen, BL Allman, RJ Salvi - Neuroscience, 2011 - Elsevier
The neuronal mechanism underlying the phantom auditory perception of tinnitus remains
elusive at present. For over 25 years, temporary tinnitus following acute salicylate …

Time course of tinnitus development following noise exposure in mice

J Turner, D Larsen, L Hughes… - Journal of …, 2012 - Wiley Online Library
Gap‐induced prepulse inhibition of acoustic startle (GPIAS) has been used in rats and mice
to study the problem of tinnitus. The current study demonstrates that similar methods can be …