The cause of insulin resistance in obesity and type 2 diabetes mellitus (T2DM) is not limited
to impaired insulin signalling but also involves the complex interplay of multiple metabolic …

Respiratory diseases are frequently characterised by epithelial injury, airway inflammation,
defective tissue repair, and airway remodelling. This may occur in a subacute or chronic …

Previous studies demonstrated that bone marrow–derived mesenchymal stem (stromal)
cells (MSCs) reduce the severity of acute lung injury in animal models and in an ex vivo …

Sustained inflammation in the brain together with microglia activation can lead to neuronal
damage. Hence limiting brain inflammation and activation of microglia is a real therapeutic …

An inflammatory response is beneficial to the organism, while an excessive uncontrolled
inflammatory response can lead to the nonspecific killing of tissue cells. Therefore …

Airborne pathogens and environmental stimuli evoke immune responses in the lung. It is
critical to health that these responses be controlled to prevent tissue damage and the …

Unexpected viral infections outbreaks, significantly affect human health, leading to
increased mortality and life disruption. Among them is the severe acute respiratory …

Resolution of inflammation is an active process involving a novel category of lipid factors
known as specialized pro-resolving lipid mediators, which includes Resolvin D1 (RvD1) …

Bacterial pneumonia is a leading cause of morbidity and mortality worldwide. Host
responses to contain infection and mitigate pathogen-mediated lung inflammation are …

While the treatment of inflammatory disorders is generally based on inhibiting factors that
drive onset of inflammation, these therapies can compromise healing (NSAIDs) or dampen …