Given the acknowledged lack of success in Alzheimer's disease (AD) drug development
over the past two decades, the objective of this review was to derive key insights from the …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by decreased
synaptic transmission and cerebral atrophy with appearance of amyloid plaques and …

Alzheimer's Disease (AD) is the most common form of dementia, affecting almost 50 million
of people around the world, characterized by a complex and age-related progressive …

Alzheimer's disease (AD) is one of the most common forms of dementia among elder
people, which is a progressive neurodegenerative disease that results from a chronic loss of …

Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

Alzheimer's disease (AD), a multifactorial complex neural disorder, is categorized with
progressive memory loss and cognitive impairment as main clinical features. The multitarget …

Alzheimer's disease (AD) is the most common form of dementia affecting specifically older
population. AD is an irreversible neurodegenerative CNS disorder associated with complex …

The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …

Alzheimer's disease (AD) is a progressive neurodegenerative disease that is difficult to treat.
Extracellular amyloid is the principal pathological criterion for the diagnosis of AD. Amyloid β …

Tau plays an important pathological role in a group of neurodegenerative diseases called
tauopathies, including Alzheimer's disease, Pick's disease, chronic traumatic …