[HTML][HTML] Pyrrolizidine alkaloids: biosynthesis, biological activities and occurrence in crop plants

S Schramm, N Köhler, W Rozhon - Molecules, 2019 - mdpi.com
Pyrrolizidine alkaloids (PAs) are heterocyclic secondary metabolites with a typical
pyrrolizidine motif predominantly produced by plants as defense chemicals against …

Ethnomedicinal uses, phytochemistry, and biological activities of plants of the genus Gynura

MS Bari, L Khandokar, E Haque, B Romano… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance The genus Gynura (Compositae) includes around
46 species and is native to the tropical regions of Southeast Asia, Africa and Australia. Many …

[HTML][HTML] In vitro evaluation of immunomodulatory, anti-diabetic, and anti-cancer molecular mechanisms of Tribulus terrestris extracts

A Khalid, T Nadeem, MA Khan, Q Ali, M Zubair - Scientific Reports, 2022 - nature.com
Dampened immunity and impaired wound healing in diabetic patients may lead to diabetic
foot ulcer disease, which is the leading cause of limb amputations and hospitalization. On …

[HTML][HTML] Cat's whiskers (Orthosiphon stamineus) tea modulates arthritis pathogenesis via the angiogenesis and inflammatory cascade

YM Tabana, FSR Al-Suede, MBK Ahamed… - … and alternative medicine, 2016 - Springer
Background Orthosiphon stamineus is used traditionally to treat gout, arthritis, and
inflammatory related conditions. The in vitro anti-inflammatory effects of the plant have been …

Traditional uses, phytochemistry, pharmacology and toxicology of the genus Gynura (Compositae): a comprehensive review

X Meng, J Li, M Li, H Wang, B Ren, J Chen… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Gynura cass., belonging to the tribe Senecoineae of the
family Compositae, contains more than 40 accepted species as annual or perennial herbs …

Quercetin and baicalein suppress monocrotaline-induced hepatic sinusoidal obstruction syndrome in rats

J Zhang, Y Sheng, L Shi, Z Zheng, M Chen… - European Journal of …, 2017 - Elsevier
Hepatic sinusoidal obstruction syndrome (SOS) is a rare liver disease with considerable
mortality. This study is designed to observe the protection of quercetin and baicalein against …

[HTML][HTML] Antioxidant and Anti-Inflammatory Effects of Genus Gynura: A Systematic Review

JN Tan, S Mohd Saffian, F Buang, Z Jubri… - Frontiers in …, 2020 - frontiersin.org
Background: Gynura species have been used traditionally to treat various ailments, such as
fever, pain, and to control blood glucose level. This systematic review critically discusses …

Inhibition of biofilm formation, quorum sensing and other virulence factors in Pseudomonas aeruginosa by polyphenols of Gynura procumbens leaves

Z Nain, FJ Mansur, SB Syed, MA Islam… - Journal of …, 2022 - Taylor & Francis
Quorum sensing (QS) enables virulence factors in bacteria for biofilm formation and
pathogenic invasion. Therefore, quorum quenching (QQ), disruption of QS circuit, becomes …

Hepatic sinusoidal obstruction syndrome caused by the ingestion of Gynura segetum in a patient with alcoholic cirrhosis: a case report

P Cen, J Ding, J Jin - Journal of International Medical …, 2021 - journals.sagepub.com
Hepatic sinusoidal obstruction syndrome (HSOS) is a rare hepatic vascular disorder
characterized by intrahepatic congestion, liver injury, and post-sinusoidal portal …

[HTML][HTML] Investigation of Gynura segetum root extract (GSrE) induced hepatotoxicity based on metabolomic signatures and microbial community profiling in rats

X Gu, S Li, M Lu, Y Li, Q Wang, L Chen, Y Jia… - Frontiers in …, 2022 - frontiersin.org
In recent years, many reports focus on the hepatotoxicity of Gynura segetum root extract
(GSrE), but the interaction between GSrE and the gut microbiota is still unclear. This study …