The utilization of recent advances in molecular and genomic technologies and progress in
pancreatic imaging techniques provided remarkable insight into genetic, environmental …

In 1788 Cawley reported on a “free living young man” who had died of emaciation and
diabetes and whose postmortem examination revealed multiple pancreatic calculi. 1 In the …

Background & Aims: Gain-of-function trypsin mutations cause acute pancreatitis and chronic
pancreatitis. Loss of trypsin inhibitor function may have similar effects. We investigated the …

BACKGROUND & AIMS:: Nonalcoholic chronic pancreatitis is usually idiopathic and often
associated with cystic fibrosis gene (CFTR) mutations. It is unknown whether pancreatitis …

Pancreatic function tests are most commonly used to diagnose chronic pancreatitis. These
tests include tests which document exocrine or endocrine gland insufficiency and tests …

Background: Mutations in the PRSS1 gene explain most occurrences of hereditary
pancreatitis (HP) but many HP families have no PRSS1 mutation. Recently, an association …

Acute pancreatitis is one of the most common conditions for which emergent imaging is
indicated. Alcohol consumption and cholelithiasis are the most common causes of acute …

There are many reviews of pancreatic acinar cell function and also of pancreatic duct
function, but there is an almost total absence of synthetic reviews bringing the integrated …

Fused positron emission tomography (PET)/computed tomography (CT) is a recently
developed technology that couples the functional information of PET with the anatomic …

Background The efficacy of pancreatic enzymes in reducing pain and improving
steatorrhoea is debatable and the evidence base for their utility needs to be determined …