Potential succinate dehydrogenase inhibitors bearing a novel pyrazole-4-sulfonohydrazide scaffold: molecular design, antifungal evaluation, and action mechanism

JQ Chai, YD Mei, L Tai, XB Wang, M Chen… - Journal of Agricultural …, 2023 - ACS Publications
Aiming to develop novel antifungal agents with a distinctive molecular scaffold targeting
succinate dehydrogenase (SDH), 24 N′-phenyl-1 H-pyrazole-4-sulfonohydrazide …

Design, synthesis, and structure–activity relationship of economical triazole sulfonamide aryl derivatives with high fungicidal activity

J Lin, S Zhou, JX Xu, WQ Yao, GF Hao… - Journal of Agricultural …, 2020 - ACS Publications
Plant fungal diseases have caused great decreases in crop quality and yield. As one of the
considerable agricultural diseases, cucumber downy mildew (CDM) caused by …

Primary Mode of Action of the Novel Sulfonamide Fungicide against Botrytis cinerea and Field Control Effect on Tomato Gray Mold

X Yan, S Chen, W Sun, X Zhou, D Yang… - International Journal of …, 2022 - mdpi.com
Botrytis cinerea is considered an important plant pathogen and is responsible for significant
crop yield losses. With the frequent application of commercial fungicides, B. cinerea has …

Synthesis and biological activity of novel hydantoin cyclohexyl sulfonamide derivatives as potential antimicrobial agents in agriculture

W Liu, S Zhang, L Xiao, Y Wan, L He… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND Plant disease is one of the most serious problems in agriculture that can
damage crops. Chemical fungicides are widely used to control plant diseases, but have led …

Discovery of 1, 2, 4-triazole-1, 3-disulfonamides as dual inhibitors of mitochondrial complex II and complex III

H Cheng, YQ Shen, XY Pan, YP Hou, QY Wu… - New Journal of …, 2015 - pubs.rsc.org
Respiratory chain succinate-ubiquinone oxidoreductase (SQR or complex II) and
ubihydroquinone-cytochrome (cyt) c oxidoreductase (cyt bc1 or complex III) have been …

Novel sulfonamides against Botrytis cinerea with no positive cross-resistance to commercial fungicides: Design, synthesis and SAR study

N Cai, L He, K Wang, Z Feng, Z Cui, M Ji, Z Qi… - Bioorganic & Medicinal …, 2020 - Elsevier
Thirty-four novel compounds were synthesized using chesulfamide (N-(2-trifluoromethyl-4-
chlorophenyl)-2-oxocyclohexyl sulfonamide), a high-profile fungicide, as the lead …

Design, Synthesis and Structure-Activity Relationship of Novel Pinacolone Sulfonamide Derivatives against Botrytis cinerea as Potent Antifungal Agents

C Liu, X Xiang, Y Wan, J Yang, Y Li, X Zhang, Z Qi… - Molecules, 2022 - mdpi.com
To develop new fungicides with high efficiency, 46 novel sulfonamide derivatives were
designed and synthesized by introducing pinacolone fragment into chesulfamide which was …

Design, synthesis and fungicidal activity of novel 2-substituted aminocycloalkylsulfonamides

C Liu, X Yan, M Wang, P Qin, Z Qi, M Ji, X Liu… - Bioorganic & Medicinal …, 2017 - Elsevier
A series of novel 2-substituted aminocycloalkylsulfonamides were designed and
synthesized by highly selective N-alkylation reaction, whose structures were characterized …

Ruthenium trichloride catalyzed synthesis of 2, 3-unsaturated-N-glycosides via Ferrier azaglycosylation

TR Reddy, S Chittela, S Kashyap - Tetrahedron, 2014 - Elsevier
An efficient, economical and mild protocol for the synthesis of 2, 3-unsaturated-N-glycosides
has been developed using ruthenium (III) chloride. The Ferrier azaglycosylation of glycals …

Ionic liquid-supported synthesis of sulfonamides and carboxamides

MK Muthayala, BS Chhikara, K Parang… - ACS Combinatorial …, 2012 - ACS Publications
An ionic liquid-supported aldehyde was designed and converted to ionic liquid-supported
secondary aryl amines through reductive amination. The reaction of ionic liquid-supported …