Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

Understanding the functional consequences of genetic variation, and how it affects complex
human disease and quantitative traits, remains a critical challenge for biomedicine. We …

Obesity is a worldwide epidemic that predisposes individuals to cardiometabolic
complications, such as type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease …

Importance Genetic and lifestyle factors both contribute to the risk of developing
cardiovascular disease, but whether poor health behaviors are associated with similar …

Abstract The Psychiatric Genomics Consortium-Posttraumatic Stress Disorder group (PGC-
PTSD) combined genome-wide case–control molecular genetic data across 11 multiethnic …

During the last decade, there have been substantial advances in the identification and
characterization of DNA sequence variants associated with individual predisposition to type …

Type 2 diabetes is a serious and common chronic disease resulting from a complex
inheritance-environment interaction along with other risk factors such as obesity and …

Abstract The National Human Genome Research Institute (NHGRI) Catalog of Published
Genome-Wide Association Studies (GWAS) Catalog provides a publicly available manually …

Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL)
cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for …

OBJECTIVE: This article examines the foundation of β-cell failure in type 2 diabetes (T2D)
and suggests areas for future research on the underlying mechanisms that may lead to …