Neuropathogenesis of delirium: review of current etiologic theories and common pathways

JR Maldonado - The American Journal of Geriatric Psychiatry, 2013 - Elsevier
Delirium is a neurobehavioral syndrome caused by dysregulation of neuronal activity
secondary to systemic disturbances. Over time, a number of theories have been proposed in …

Delirium in elderly adults: diagnosis, prevention and treatment

TG Fong, SR Tulebaev, SK Inouye - Nature Reviews Neurology, 2009 - nature.com
Delirium is a common and serious acute neuropsychiatric syndrome with core features of
inattention and global cognitive dysfunction. The etiologies of delirium are diverse and …

Delirium in older persons

SK Inouye - New England journal of medicine, 2006 - Mass Medical Soc
The prevalence of delirium increases sharply with age, and about 20 percent of older
patients have delirium at the time of hospital admission for any reason. This review …

Diagnosing delirium in older emergency department patients: validity and reliability of the delirium triage screen and the brief confusion assessment method

JH Han, A Wilson, EE Vasilevskis, A Shintani… - Annals of emergency …, 2013 - Elsevier
Study objective Delirium is a common form of acute brain dysfunction with prognostic
significance. Health care professionals caring for older emergency department (ED) patients …

Pathoetiological model of delirium: a comprehensive understanding of the neurobiology of delirium and an evidence-based approach to prevention and treatment

JR Maldonado - Critical care clinics, 2008 - Elsevier
Delirium is the most common complication found in the general hospital setting. Yet, we
know relatively little about its actual pathophysiology. This article contains a summary of …

Quality of discharge practices and patient understanding at an academic medical center

LI Horwitz, JP Moriarty, C Chen, RL Fogerty… - JAMA internal …, 2013 - jamanetwork.com
Importance With growing national focus on reducing readmissions, there is a need to
comprehensively assess the quality of transitional care, including discharge practices …

Comprehensive geriatric assessment in the emergency department

G Ellis, T Marshall, C Ritchie - Clinical interventions in aging, 2014 - Taylor & Francis
Changing global demography is resulting in older people presenting to emergency
departments (EDs) in greater numbers than ever before. They present with greater urgency …

Preventable medical injuries in older patients

JM Rothschild, DW Bates… - Archives of internal …, 2000 - jamanetwork.com
Injuries associated with hospitalization are more common in older (≥ 65 years) than in
younger patients (< 65 years), and they may be more severe and more often preventable …

Prevention of delirium in hospitalized older patients: risk factors and targeted intervention strategies

SK Inouye - Annals of medicine, 2000 - Taylor & Francis
Delirium is a common, costly, and potentially devastating condition for hospitalized older
patients. Delirium is a multifactorial syndrome, involving the inter-relationship between …

Altered mental status in older patients in the emergency department

JH Han, ST Wilber - Clinics in geriatric medicine, 2013 - geriatric.theclinics.com
Altered mental status is a common chief complaint among older patients in the emergency
department (ED). Despite the frequency of this complaint, the term “altered mental status” is …