[HTML][HTML] Staphylococcus aureus biofilm: Formulation, regulatory, and emerging natural products-derived therapeutics

X Wu, H Wang, J Xiong, GX Yang, JF Hu, Q Zhu… - Biofilm, 2024 - Elsevier
Staphylococcus aureus can readily form biofilm which enhances the drug-resistance,
resulting in life-threatening infections involving different organs. Biofilm formation occurs due …

Sodium alginate/polyvinyl alcohol nanofibers loaded with Shikonin for diabetic wound healing: In vivo and in vitro evaluation

C Ding, J Yang, N Wang, Q Ding, S Sun, Y Gao… - International journal of …, 2024 - Elsevier
Diabetic wounds are typically chronic wounds and the healing process is limited by
problems such as high blood glucose levels, bacterial infections, and other issues that make …

An effective antimicrobial strategy of colistin combined with the Chinese herbal medicine shikonin against colistin-resistant Escherichia coli

Y Liu, Y Wang, J Kong, X Jiang, Y Han… - Microbiology …, 2023 - Am Soc Microbiol
The treatment of bacterial infections has become more challenging due to the increasing
prevalence of colistin-resistant (Col-R) pathogens. Shikonin is a Chinese herbal medicine …

The anti-leukemia activity and mechanisms of shikonin: a mini review

H Dong, CD Chang, F Gao, N Zhang, XJ Yan… - Frontiers in …, 2023 - frontiersin.org
Leukemia encompasses a group of highly heterogeneous diseases that pose a serious
threat to human health. The long-term outcome of patients with leukemia still needs to be …

Promiscuous Lipase-Catalyzed Knoevenagel–Phospha–Michael Reaction for the Synthesis of Antimicrobial β-Phosphono Malonates

J Samsonowicz-Górski, D Koszelewski… - International Journal of …, 2022 - mdpi.com
An enzymatic route for phosphorous–carbon bond formation was developed by discovering
new promiscuous activity of lipase. We reported a new metal-free biocatalytic method for the …

Inhibition of Biofilm Formation in Cutibacterium acnes, Staphylococcus aureus, and Candida albicans by the Phytopigment Shikonin

YG Kim, JH Lee, S Kim, S Park, YJ Kim… - International Journal of …, 2024 - mdpi.com
Skin microbiota, such as acne-related Cutibacterium acnes, Staphylococcus aureus, and
fungal Candida albicans, can form polymicrobial biofilms with greater antimicrobial …

Ruthenium polypyridine complexes containing prenyl groups as antibacterial agents against Staphylococcus aureus through a membrane‐disruption mechanism

R Wang, X Zhou, J Chen, Y Chen, Y Xiong… - Archiv der …, 2023 - Wiley Online Library
Four new ruthenium polypyridyl complexes with prenyl groups,[Ru (bpy) 2 (MHIP)](PF6) 2
(Ru (II)‐1),[Ru (dtb) 2 (MHIP)](PF6) 2 (Ru (II)‐2),[Ru (dmb) 2 (MHIP)](PF6) 2 (Ru (II)‐3), and …

Rapid formed temperature-sensitive hydrogel for the multi-effective wound healing of deep second-degree burn with shikonin based scar prevention

D Bai, H Cheng, J Mei, G Tian, Q Wang, S Yu… - Biomaterials …, 2024 - Elsevier
Burns are a significant public health issue worldwide, resulting in prolonged hospitalization,
disfigurement, disability and, in severe cases, death. Among them, deep second-degree …

Endophytes: a uniquely tailored source of potential antibiotic adjuvants

AY Moussa - Archives of Microbiology, 2024 - Springer
Multidrug microbial resistance is risking an annual loss of more than 10 million people'lives
by 2050. Solutions include the rational use of antibiotics and the use of drugs that reduce …

Exploring the Synergistic Effect of Thymol with Oxacillin against Methicillin Resistant Staphylococcus aureus

HK Sharma, A Karna, SK Verma, P Gupta… - Indian Journal of …, 2024 - Springer
The rise of antibiotic resistance in recent years poses a major challenge in the management
of bacterial infections caused by Staphylococcus aureus (S. aureus), especially methicillin …