Cancer immunotherapy (CIT) with antibodies targeting the programmed cell death 1 protein
(PD-1)/programmed cell death 1 ligand 1 (PD-L1) axis have changed the standard of care in …

Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

Despite advances in diagnosis and therapy, an individual with ovaries carries an
approximate 1 in 108 lifetime chance to die due to ovarian cancer (OC). Primary therapy …

Simple Summary DNA damage is one of the hallmarks of cancer. Epithelial ovarian cancer
(EOC)—especially the high-grade serous subtype—harbors a defect in at least one DNA …

Ovarian cancer (OC) is an aggressive gynecological tumor usually diagnosed with
widespread metastases and ascites. Here, we depicted a single-cell landscape of the OC …

Importance Ovarian cancer has the highest mortality rate among gynecologic malignant
tumors. Data are lacking on the survival benefit of hyperthermic intraperitoneal …

Background Ovarian cancer (OC) is one of the most common and most malignant
gynecological malignancies in gynecology. On the other hand, dysregulation of copper …

Epithelial ovarian cancer (EOC) is one of the cancers most influenced by hereditary factors.
A fourth to a fifth of unselected EOC patients carry pathogenic variants (PVs) in a number of …

Ovarian cancer is the deadliest gynecologic cancer. Despite recent advances, clinical
outcomes remain poor, necessitating novel therapeutic approaches. To investigate …

Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …