Artificial intelligence (AI) is being increasingly adopted in medical research and applications.
Medical AI devices have continuously been approved by the Food and Drug Administration …

Objective: We aimed to construct the ferritin autophagy regulatory network and illustrate its
mechanism in ferroptosis, TME immunity and malignant phenotypes of ovarian cancer …

Relevance The pathogenesis and biomarkers of ovarian cancer (OC) remain not well-known
in diagnosis, effective therapy, and prognostic assessment in OC personalized medicine …

Nanomaterials that mimic the catalytic activity of natural enzymes in the complex biological
environment of the human body are called nanozymes. Recently, nanozyme systems have …

Summary Background The Wee1 (WEE1hu) inhibitor adavosertib and gemcitabine have
shown preclinical synergy and promising activity in early phase clinical trials. We aimed to …

Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …

Simple Summary Ovarian cancer is a lethal gynecologic tumor and is generally resistant to
conventional treatments. Stable cancer-associated fibroblasts (CAFs) are important cellular …

Ovarian cancer is a high-mortality malignancy in women. The contemporary clinical
chemotherapy with classic cytotoxic drugs, targeted molecular inhibitors would mostly fail …

Tumor metastasis and recurrence is one of the biggest problems in curing cancers. Due to
the difficulty in complete removal of the primary tumor in traditional surgeries and the poor …

Ovarian cancer is the fifth cause of cancer-related deaths in women with high grade serous
carcinoma (HGSOC) representing the most common histological subtype. Approximately …