Adeno-associated virus (AAV) has emerged as a pivotal delivery tool in clinical gene
therapy owing to its minimal pathogenicity and ability to establish long-term gene expression …

In December 1983, a seminal paper appeared on the overexpression of human IFN-β in
insect cells with a genetically engineered baculovirus. The finding that baculoviruses …

Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

EFSA is requested to assess the safety of a broad range of biological agents in the context of
notification for market authorisation as sources of food and feed additives, food enzymes …

Researchers have applied mesenchymal stem cells (MSC) to a variety of therapeutic
scenarios by harnessing their multipotent, regenerative, and immunosuppressive properties …

Adeno-associated virus (AAV) has shown promising therapeutic efficacy with a good safety
profile in a wide range of animal models and human clinical trials. With the advent of …

The potential of clustered regularly interspaced short palindromic repeats (CRISPR)–
CRISPR associated protein 9 (Cas9)-based therapeutic genome editing is hampered by …

The baculovirus‐insect cell expression system is widely used in producing recombinant
proteins. This review is focused on the use of this expression system in developing …

Autoimmune/inflammatory diseases affect many people and are an important cause of
global incidence and mortality. Mesenchymal stem cells (MSCs) have low immunogenicity …

CRISPR/Cas9 system exploits the concerted action of Cas9 nuclease and programmable
single guide RNA (sgRNA), and has been widely used for genome editing. The Cas9 …